N/A
N=219
Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Respiratory Failure · Mechanical Ventilation · Acute Lung Injury
Bottom Line
View on ClinicalTrials.gov: NCT01628523 ↗Enrolled (actual)
219
Serious AEs
0.0%
Results posted
Mar 2020
Primary outcome: Primary: To Further Characterize ED Mechanical Ventilation — 500 mL
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- For inclusion in the study, patients will have to require mechanical ventilation either via an endotracheal tube or tracheostomy tube. (Other)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Washington University School of Medicine
- Primary completion
- Aug 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY To Further Characterize ED Mechanical Ventilation |
500 | — |
| SECONDARY The Incidence of ARDS in Mechanically Ventilated Emergency Department Patients, and Risk Factors Associated With Progression to ARDS |
30 | <0.05 sig |
Summary
Despite its life-saving potential, the mechanical ventilator has great potential to do harm. Despite years of research, the mortality in acute lung injury (ALI) remains very high. Treatment options after ALI onset are very limited, therefore prevention may be the best option. Unfortunately, the emergency department has not been studied with respect to mechanical ventilation practices, and its contribution to ALI is unknown. The investigators hypothesize that mechanical ventilation is frequently used in the ED and for a variety of reasons, and that ED mechanical ventilation has an effect on long term outcomes.
Eligibility Criteria
Inclusion Criteria
- Ventilation either via an endotracheal tube or tracheostomy
Exclusion Criteria
- Non-invasive positive pressure ventilation;
- Death in the immediate post-intubation phase of care;
- Chronic ventilator-dependence, either at home or extended care facility.
Data sourced from ClinicalTrials.gov (NCT01628523). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.