Increasing midazolam sedation levels associated with decreased energy expenditure in mechanically ventilated patients
Deep sedation reduces energy use in critically ill patients
In this prospective self-controlled study of 74 critically ill patients requiring mechanical ventilation, increasing levels of midazolam sed…
Deep sedation levels can lower how much energy the body burns in patients using mechanical ventilation.
Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients.
A Common ICU Infection Strategy Fails Its Biggest Test
This randomized trial involving 9,289 critically ill patients across 26 ICUs in Australia and Canada evaluated Selective Decontamination of …
A massive ICU trial found that wiping out gut bacteria in ventilated patients reduced infections but did not save more lives.
Low-use wrist-strap restraint strategy did not improve days free of delirium or coma compared with high-use strategy in mechanically ventilated adults.
ICU Wrist Restraints: The Surprising Truth About Using Fewer
This randomized clinical trial evaluated a restrictive, low-use wrist-strap physical restraint strategy versus a liberal, high-use strategy …
A major ICU trial found that using fewer wrist restraints did not help patients stay more alert or avoid confusion while on breathing machin…
Diaphragm ultrasound combined with D-RSBI predicts weaning outcomes in neurocritical patients on mechanical ventilation.
An Ultrasound May Reveal When Patients Can Breathe Alone
This retrospective analysis examined 128 patients with severe neurological conditions on mechanical ventilation at a Chongqing neurosurgery …
A simple bedside ultrasound of the main breathing muscle, paired with a breath-counting ratio, helped doctors tell who was ready to breathe …
Early supplemental parenteral nutrition may reduce ventilation time and ICU stay in older underfed ICU patients
Early nutrition support linked to shorter ICU stays for older patients on ventilators
A randomized trial in 92 older ICU patients requiring mechanical ventilation and achieving <50% of enteral nutrition targets found that earl…
Starting IV nutrition on day three instead of day seven helped older ICU patients on breathing machines spend less time on ventilators and i…
Nurse-led sedation protocols reduce mortality and delirium in mechanically ventilated ICU patients
Nurse-led sedation protocols in intensive care may reduce patient mortality and complications
A systematic review and meta-analysis of 16 RCTs involving 1,887 mechanically ventilated ICU patients found nurse-led sedation protocols sig…
Nurse-led sedation protocols in intensive care significantly reduce patient death, confusion, and hospital stay length for those on breathin…
Inspiratory muscle training shows no clear effect on physical function in critically ill adults on mechanical ventilation
Breathing muscle training shows uncertain effect on physical function in ICU patients
A systematic review and meta-analysis of 18 studies in adults requiring invasive mechanical ventilation for ≥24 hours found inspiratory musc…
Breathing muscle training for ICU patients on ventilators may not improve their ability to move and perform daily activities, with effects r…