Meta-analysis of remimazolam versus propofol in mechanically ventilated ICU patients
New ICU Sedative Cuts Patient Side Effects Without Raising Risks
This meta-analysis of randomized controlled trials compared remimazolam to propofol in mechanically ventilated ICU patients. It found no sig…
A safer sedative option for ICU patients on ventilators reduces dangerous confusion and side effects while matching current treatments in su…
Meta-analysis finds high mortality and morbidity for neonates on mechanical ventilation in low-resource settings
Over half of newborns on life support in poor areas still die in the hospital
A systematic review and prognostic meta-analysis examined outcomes for neonates receiving invasive mechanical ventilation in low-resource se…
A major review found that more than 40 percent of newborns needing breathing machines in low-resource settings do not survive their hospital…
Selective decontamination of the digestive tract reduces hospital mortality in mechanically ventilated ICU adults
Selective decontamination lowers death risk for ICU patients on ventilators
This systematic review and meta-analysis evaluated selective decontamination of the digestive tract (SDD) versus standard care or placebo in…
A massive analysis of 32 studies shows selective decontamination of the digestive tract lowers hospital death rates for adults on ventilator…
Non-routine GRV monitoring does not increase feeding intolerance in ventilated adults
Nurses Can Cut Daily Checks Without Hurting Feeding Plans
This randomized non-inferiority trial compared non-routine (once daily) versus routine 4-hourly gastric residual volume (GRV) monitoring in …
Cutting daily stomach checks saves nursing time without causing more vomiting or feeding problems for ICU patients.
Increasing midazolam sedation levels associated with decreased energy expenditure in mechanically ventilated patients
Deep sedation reduces energy use in critically ill patients
In this prospective self-controlled study of 74 critically ill patients requiring mechanical ventilation, increasing levels of midazolam sed…
Deep sedation levels can lower how much energy the body burns in patients using mechanical ventilation.
Meta-analysis of ketamine versus other analgosedatives in critically ill children receiving invasive mechanical ventilation
Ketamine cuts opioid use in ventilated kids
This systematic review and meta-analysis evaluated continuous ketamine infusion compared with other analgosedatives in critically ill childr…
A new analysis suggests ketamine could help reduce opioid use in children on breathing machines, offering a safer path to pain control in in…
Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients
A Common ICU Infection Strategy Fails Its Biggest Test
This randomized trial involving 9,289 critically ill patients across 26 ICUs in Australia and Canada evaluated Selective Decontamination of …
A massive ICU trial found that wiping out gut bacteria in ventilated patients reduced infections but did not save more lives.
Low-use wrist-strap restraint strategy did not improve days free of delirium or coma compared with high-use strategy in mechanically ventilated adults
ICU Wrist Restraints: The Surprising Truth About Using Fewer
This randomized clinical trial evaluated a restrictive, low-use wrist-strap physical restraint strategy versus a liberal, high-use strategy …
A major ICU trial found that using fewer wrist restraints did not help patients stay more alert or avoid confusion while on breathing machin…
Diaphragm ultrasound combined with D-RSBI predicts weaning outcomes in neurocritical patients on mechanical ventilation
An Ultrasound May Reveal When Patients Can Breathe Alone
This retrospective analysis examined 128 patients with severe neurological conditions on mechanical ventilation at a Chongqing neurosurgery …
A simple bedside ultrasound of the main breathing muscle, paired with a breath-counting ratio, helped doctors tell who was ready to breathe …
Early supplemental parenteral nutrition may reduce ventilation time and ICU stay in older underfed ICU patients
Early nutrition support linked to shorter ICU stays for older patients on ventilators
A randomized trial in 92 older ICU patients requiring mechanical ventilation and achieving <50% of enteral nutrition targets found that earl…
Starting IV nutrition on day three instead of day seven helped older ICU patients on breathing machines spend less time on ventilators and i…
Nurse-led sedation protocols reduce mortality and delirium in mechanically ventilated ICU patients
Nurse-led sedation protocols in intensive care may reduce patient mortality and complications
A systematic review and meta-analysis of 16 RCTs involving 1,887 mechanically ventilated ICU patients found nurse-led sedation protocols sig…
Nurse-led sedation protocols in intensive care significantly reduce patient death, confusion, and hospital stay length for those on breathin…
Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients
Small pilot study tests sleep environment intervention for ventilated ICU patients
A pilot randomized controlled trial in 17 mechanically ventilated ICU patients with minimal sedation assessed the feasibility of a multi-com…
A small Chilean ICU study shows that dynamic lights, sound masking, and grouped care checks are feasible ways to help ventilated patients sl…
Questions about Mechanical Ventilation
Can ultrasound of the diaphragm predict if a neurocritical patient on mechanical ventilation will breathe on their own?
Yes, diaphragm ultrasound combined with the Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) can predict weaning success in neurocritical patients on mechanical ventilation, though more research is needed.
Full answer →Does using fewer wrist straps help adults on mechanical ventilation stay awake more often?
No, a low-use wrist-strap strategy did not improve days free of delirium or coma compared to a high-use strategy in mechanically ventilated adults.
Full answer →Did selective decontamination of the digestive tract show any benefit over standard care for mechanical ventilation patients?
Yes, selective decontamination of the digestive tract (SDD) likely reduces hospital mortality in mechanically ventilated ICU patients, though results vary across studies.
Full answer →Does selective decontamination of the digestive tract reduce death risk for adults on mechanical ventilation?
Yes, selective decontamination of the digestive tract (SDD) likely reduces hospital mortality in mechanically ventilated ICU adults, based on a large meta-analysis showing a 9% relative risk reduction.
Full answer →All Mechanical Ventilation Articles
- Meta-analysis of remimazolam versus propofol in mechanically ventilated ICU patients
- Meta-analysis finds high mortality and morbidity for neonates on mechanical ventilation in low-resource settings
- Selective decontamination of the digestive tract reduces hospital mortality in mechanically ventilated ICU adults
- Non-routine GRV monitoring does not increase feeding intolerance in ventilated adults
- Increasing midazolam sedation levels associated with decreased energy expenditure in mechanically ventilated patients
- Meta-analysis of ketamine versus other analgosedatives in critically ill children receiving invasive mechanical ventilation
- Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients
- Low-use wrist-strap restraint strategy did not improve days free of delirium or coma compared with high-use strategy in mechanically ventilated adults
- Diaphragm ultrasound combined with D-RSBI predicts weaning outcomes in neurocritical patients on mechanical ventilation
- Early supplemental parenteral nutrition may reduce ventilation time and ICU stay in older underfed ICU patients
- Nurse-led sedation protocols reduce mortality and delirium in mechanically ventilated ICU patients
- Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients
- Inspiratory muscle training shows no clear effect on physical function in critically ill adults on mechanical ventilation