N/A
N=80
Effects of Obesity Treatments on Food Preferences and Metabolism
Obesity · Type 2 Diabetes Mellitus
Bottom Line
View on ClinicalTrials.gov: NCT01724060 ↗Enrolled (actual)
80
Serious AEs
0.0%
Results posted
Mar 2020
Primary outcome: Primary: Change in Energy Intake From Baseline — 500; 310; 482; 5 kcal
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Imperial College London
- Primary completion
- Oct 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Energy Intake From Baseline |
500; 310; 482; 5; 27; 103 | — |
| SECONDARY Change in Appetite Ratings From Baseline |
— | — |
| SECONDARY Change in Metabolites From Baseline |
— | — |
| SECONDARY Change in Hepatic Insulin Resistance From Baseline |
— | — |
| SECONDARY Change in Macronutrient Composition From Baseline |
— | — |
Summary
Obesity and Type 2 Diabetes Mellitus are major health problems which are becoming a burden both for patients and health systems alike. The surgical and medical treatments available for these conditions have improved significantly in the last two decades. The investigators do not however know how these treatments compare to each other and how they act in the body to cause weight loss and diabetes improvements. The studies of this experiment are complementary to each other. They aim to answer related questions and will allow us to study how these treatments work and eventually develop safer and more effective therapies for obesity and diabetes.
Eligibility Criteria
Inclusion Criteria
- Adult patients with overweight and/or obesity (BMI ≥30 Kg/m2) who are eligible for obesity treatment based on NICE guidance or that are having non bariatric surgery or endoscopy.
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT01724060). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.