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N/A N=90 Randomized Treatment

Homebased Training With Telemonitoring Guidance in Low to Moderate Risk Patients Entering Cardiac Rehabilitation

Acute Coronary Syndrome · Myocardial Infarction

Enrolled (actual)
90
Serious AEs
13.3%
Results posted
Aug 2019
Primary outcome: Primary: Physical Fitness — 24.4; 24.0; 27.9; 26.5 ml O2/kg/min

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Home-based training (Behavioral); Centre-based training (Behavioral)
Age
Pediatric, Adult, Older Adult
Sex
All
Sponsor
Maxima Medical Center
Primary completion
Oct 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Physical Fitness
24.4; 24.0; 27.9; 26.5; 27.7; 27.5
PRIMARY
Physical Activity Level (PAL)
2.09; 1.95; 2.22; 2.38; 2.14; 2.13
SECONDARY
Training Adherence
22.0; 20.6
SECONDARY
Health Related Quality of Life
5.62; 5.45; 6.00; 5.90; 5.75; 5.43
SECONDARY
Patient Satisfaction
8.7; 8.1

Summary

Physical exercise training appears effective for low to moderate patients assigned to cardiac rehabilitation. However, adherence to cardiac rehabilitation is low and physical activity levels often drop after attending the last supervised rehabilitation session. This study will compare home based physical exercise training including telemonitoring with regular centre based physical exercise training. Main outcome measures are the change in physical activity and the change in physical fitness (peak Oxygen uptake) after the initial rehabilitation period (12 weeks) and after 1 year. Secondary outcome measures are cost-effectiveness, training adherence, health-related quality of life and patient satisfaction.

Eligibility Criteria

Inclusion criteria

  • Patients with an ACS (including non ST and ST elevation myocardial infarction and unstable angina) or a cardiac revascularization procedure (PCI or CABG) entering outpatient CR at Maxima Medical Center.
  • Indication for exercise training according to the Dutch clinical algorithm for assessment of patient needs in cardiac rehabilitation.
  • Internet access and PC at home (i.e. more than 90 percent of the Dutch household)

Exclusion criteria

  • High risk according to the Dutch CR practice guideline.
  • Systolic heart failure (left ventricular ejection fraction of more than 40 percent.
  • New York Heart Association class III-IV (i.e. breathlessness during light exercise or at rest).
  • Severe arrhythmia.
  • Hemodynamically significant valvular disease.
  • Implantable cardioverter-defibrillator (ICD) implantation
  • Heart transplantation.
  • Chronic angina or silent ischemia.
  • Comorbidity impairing exercise capacity (e.g. COPD, diabetes mellitus, peripheral vascular disease and orthopedic or neurological conditions).
  • Severe psychological or cognitive impairments.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01732419). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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