N/A N=300 Randomized Double-blind Treatment

The Effect of Complementary Medicine (CAM) Treatments on Common Symptoms in Hospitalized Patients

Pain · Nausea · Anxiety

Bottom Line

View on ClinicalTrials.gov: NCT01733771 ↗

Enrolled (actual)

300

Serious AEs

0.0%

Results posted

May 2025

Primary outcome: Primary: Perioperative Anxiety Expressed in Visual Analogue Scale for Anxiety (VAS-A) From 0 (Asymptomatic: no Anxiety) to 10 Extremely Symptomatic Anxiety — -2.83; 0.24; -1.99 units on VAS-A scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Reflexology (Other); Sham reflexology (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Bnai Zion Medical Center
Primary completion: Dec 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Perioperative Anxiety Expressed in Visual Analogue Scale for Anxiety (VAS-A) From 0 (Asymptomatic: no Anxiety) to 10 Extremely Symptomatic Anxiety	-2.83; 0.24; -1.99	—

Summary

This is a randomized, single blinded, interventional trial conducted in patients undergoing elective laparoscopic cholecystectomy, comparing the following three groups: Controls receiving standard-of-care (SoC) only (Group 1); intervention group receiving reflexology and SoC (Group 2); and a group receiving sham reflexology and SoC (Group 3). In all groups, level of preoperative anxiety was evaluated at entry and exit from the Holding Room Area (HRA). The evaluation was carried out using the Visual Analogue Scale for Anxiety (VAS-A) questionnaire.

Eligibility Criteria

Inclusion Criteria

Patients aged 18 years
Undergoing Laparoscopic Cholecysyectomy (LC)

Exclusion criteria

Patients with a history of obstructive sleep apnea
Contraindication for benzodiazepines
Hemodynamic instability
Leg ulcers
Patients undergoing a LC together with another surgical procedure.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01733771). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.