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N/A N=30 Randomized Quadruple-blind Treatment

Spinal Cord Stimulation Frequency Study

Failed Back Surgery Syndrome

Enrolled (actual)
30
Serious AEs
2.1%
Results posted
Dec 2017
Primary outcome: Primary: Visual Analog Scale (VAS) on Back Pain — 4.83; 4.51; 4.57; 3.22 units on a scale — p=0.002

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Sham (Device); 1200 Hz (Device); 3030 Hz (Device); 5882 Hz (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
MedtronicNeuro
Primary completion
Aug 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Visual Analog Scale (VAS) on Back Pain
4.83; 4.51; 4.57; 3.22 0.002 sig

Summary

The purpose of this study is to evaluate the role of frequency settings on spinal cord stimulation in the management of Failed Back Surgery Syndrome (SCS Frequency Study).

Eligibility Criteria

Inclusion Criteria

  • At least 18 years old at the time of informed consent
  • Willing and able to provide a signed and dated informed consent
  • Capable of comprehending and consenting in English
  • Willing and able to comply with all study procedures, study visits, and be available for the duration of the study
  • On a stable dose (no new, discontinued or changes in) of all prescribed pain medications and willing/able to maintain or only decrease the dose of all prescribed pain medications
  • Tried appropriate conventional medical management for their pain
  • Not indicated for additional surgical treatment in the opinion of the referring physician or spinal surgeon
  • Undergone previous spinal surgery
  • Diagnosed with FBSS with appropriate pain score
  • Primary pain at appropriate spinal level

Exclusion Criteria

  • Has an active implanted device, whether turned on or off
  • Displays current signs of a systemic infection
  • Pregnant or lactating, inadequate birth control, or the possibility of pregnancy during the study
  • Has untreated major psychiatric comorbidity
  • Has serious drug-related behavioral issues
  • Has neurological abnormalities unrelated to Failed Back Surgery Syndrome
  • Diagnosed with Raynaud disease
  • Diagnosed with Fibromyalgia
  • Has any active malignancy or has been diagnosed with cancer and has not been in remission for at least 1 year prior to screening
  • Has secondary gains which, in the opinion of the investigator, are likely to interfere with the study
  • Participating or planning to participate in another clinical trial
  • Has characteristics/limits of household or close contacts involved in study (eg, family member already a study participant where blind could be broken)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01750229). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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