1 published article · Updated continuously
9 trials tracked for Failed Back Surgery Syndrome: 4 in phase 3 or 4 and 2 with published results. The most-cited published study has 149 citations.
Showing the 9 most-cited and recently-updated of 9 trials. Browse the full registry →
Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.
Optimal Medical Management (OMM) has been shown to significantly improve outcomes for patients with failed back surgery syndrome compared to alternative treatments. Specifically, OMM resulted in a significantly higher proportion of subjects achieving at least a 50% reduction in low back pain intensity (p=0.036). Patients receiving OMM also demonstrated statistically significant improvements in both low back pain intensity (p<0.001) and leg pain intensity (p<0.001) as measured by the Numeric Pain Rating Scale (NPRS) 2.
Precision Spinal Cord Stimulation (SCS) has demonstrated a reduction in Visual Analog Scale (VAS) scores from baseline to 2 weeks post-initial fitting 5. Other interventions, such as Bupivacaine, have been evaluated for pain and disability; however, specific comparative efficacy data against other standard treatments were not provided in the reported outcomes 3. Pregabalin was also studied, but results did not show statistically significant differences in pain scores (p=0.279), global impression of change (p=0.282), or Oswestry Disability Questionnaires (p=0.139) at 3 weeks 4.
AI synthesis of 6 cited trials, updated Jun 21, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.
