N/A N=158 Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
Chronic Pain
Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=304 Spinal Cord Stimulation for Low Back Pain
Chronic Pain
Primary: Effectiveness of SCS Stimulation in Reducing Back Pain Associated With Failed Back Surgery Syndrome After 12 Months of Use.
Phase 4 N=218 Spinal Cord Stimulation for Predominant Low Back Pain
Failed Back Surgery Syndrome · Back Pain · Pain in Leg, Unspecified
Primary: Compare Proportion of Subjects With ≥50% Reduction in Low Back Pain Intensity Between the Treatment Groups — 15; 5 Participants — p=0.036
N/A N=125 Evaluate St Jude Medical Prodigy Neuromodulation for FBSS or Chronic Pain of the Trunk and/or Limbs
Chronic Pain
Primary: Percentage Change From Baseline in Overall VAS at 3 Months — -51.3 Percentage change
N/A N=27 Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Laminectomy · Post-laminectomy Syndrome · Spinal Cord Syndrome
Primary: Comparing Visual Analogue Scale (VAS) — 9.3; 8.6; 5.7; 4.9 score on a scale — p=0.112
N/A N=30 Spinal Cord Stimulation Frequency Study
Failed Back Surgery Syndrome
Primary: Visual Analog Scale (VAS) on Back Pain — 4.83; 4.51; 4.57; 3.22 units on a scale — p=0.002
N/A N=269 Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
Chronic Low-Back Pain · Refractory Pain · Neuropathic Pain
Primary: The Difference in Responders Between Both Groups — 87; 5 participants — p=<0.0001
N/A N=184 Understanding Non-Response in Spine Fusion Surgery
Spine Fusion
Primary: Oswestry Disability Index — 41.3; 30.4; 19.4 score on a scale
N/A N=42 Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
Low Back Pain · Sciatica · Back Related Leg Pain
Primary: Number of Particpants Screened Per Month — 103 participants per month
N/A N=248 Postoperative Management for Degenerative Spinal Conditions
Spinal Degenerative Disorder
Primary: Oswestry Disability Index (ODI) — 43.6; 45.46; 31.31; 31.19 units on a scale
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
N/A N=241 SCS as an Option for Chronic Low Back and/or Leg Pain Instead of Surgery
Chronic Pain
Primary: Responder Rate — 51; 5 Participants
N/A N=32 The Back Exercises to Neutralize Disability Study
Low Back Pain
Primary: Trunk Extensor Muscle Cross Sectional Area % of Change — -1.7; -3.9 percentage of change
N/A N=188 Efficacy of DBM Fasciatherapy for Patients Suffering From Chronic Low Back Pain
Low Back Pain
Primary: Pain Intensity — 4.2; 4.1; 4.0 score on a scale
N/A N=60 Sacroiliac (SI) Screws: The Effect of SI Screw Removal on Patient-Reported Pain and Functional Outcomes
Sacroiliac Joint · Pain · Pelvis
Primary: Post-operative Pain Within 6 Months After Iliosacral Screw Removal Using the Brief Pain Inventory (BPI) — 3.7; 4.7 units on a scale — p==0.57
N/A N=104 Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Radiating Pain · Myelopathy · Cervicobrachial Syndrome
Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641
N/A N=39 A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
Lumbar Facet Syndrome
Primary: Numeric Pain Rating Scale (NPRS) — 14; 3 Participants
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
N/A N=30 Trial Evaluating the Safety and Effectiveness of NUBAC™ Disc Arthroplasty
Degenerative Disc Disease
Primary: Participants With Improved Patient Function — 7; 6 participants — p=1.0
N/A N=10 Postoperative Telehealth Mindfulness Intervention After Spine Surgery
Chronic Low-back Pain · Postsurgical Pain · Opioid Use
Primary: Feasibility - Study Retention — 3 Participants
Phase 4 N=45 Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
Postoperative Pain
Primary: Analgesic Requirement — 0.60 (mg/kg)
N/A N=16 Selecting Effective Combinations of Treatment for Low Back Pain
Low Back Pain
Primary: Roland-Morris Disability Questionnaire — 9.8; 5.3; 13.3; 16.7 units on a scale
N/A N=19 Changes of Pain and Functional Parameters in Back Pain Patients Over Time
Changes Over Time in Pain and Functional Parameters
Primary: Changes in Visual Analog Scale Pain Scores — 3.6; 1.2; 0.5 Units on a scale
N/A N=15 Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study
Low Back Pain
Primary: Numbers and Types of Adverse Events (Only Number of Events is Reported in This Section - See Adverse Events Section for Further Detail) — 17 Events
N/A N=56 Enhanced Recovery After Spine Surgery
Enhanced Recovery After Surgery · Spine Surgery
Primary: Patient Score on QoR40 Inventory. — 179.4; 170.3 scores on a scale
N/A N=59 Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc Disease
Degenerative Disc Disease · Lumbar Spondylosis · Low Back Pain
Primary: Pain Diary — 6.71; 5 units on a scale
N/A N=50 Study of Basivertebral Nerve Ablation Treatment of Chronic Low Back Pain
Chronic Low Back Pain
Primary: Oswestry Disability Index (ODI) - 3 Months — -30.33 units on a scale — p=<0.001
N/A N=41 Air Barrier System Device to Reduce Contamination in Posterior Spine Surgery
Surgery
Primary: CFU Density — 5.05; 1.55 CFU/m^3
N/A N=299 Evaluation of Spine Surgery Analgesic Pathway
Posterior Spine Surgery
Primary: Quality of Recovery — 109; 109 units on a scale — p=0.92
Phase 3 N=134 The Safety and Efficacy of the Buprenorphine Transdermal System (BTDS) in Subjects With Chronic Back Pain.
Back Pain
Primary: Pain on the Average, Mean Change From Baseline Days 21-84 (Last Observation Carried Forward [LOCF]) — -1.01; -1.82; -1.92 Units on a scale — p=0.0350