N/A
N=81
Effects of Different Surgical Methods to Treat Obesity
Obesity · Type 2 Diabetes · Insulin Sensitivity
Bottom Line
View on ClinicalTrials.gov: NCT01785134 ↗Enrolled (actual)
81
Serious AEs
0.0%
Results posted
Oct 2014
Primary outcome: Primary: Insulin Sensitivity at 2 Years — 6.7; 6.6 glucose/kg body weight/min
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Omentectomy (Procedure); Gastric bypass operation (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Karolinska Institutet
- Primary completion
- Dec 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Insulin Sensitivity at 2 Years |
6.7; 6.6 | — |
| SECONDARY Body Composition at Two Years |
36; 38 | — |
| SECONDARY Blood Pressure at 2 Years |
123; 121 | — |
| SECONDARY Body Mass Index at 2 Years |
28.6; 28.9 | — |
| SECONDARY Blood Lipids |
4.0; 4.2 | — |
Summary
Obese patients have an increased risk for developing severe metabolic disorders. This risk can only partly be reduced by weight reduction. The investigators have in a pilot study investigated if removal of abdominal fat (visceral) in addition to weight loss has additional beneficial effects on the metabolic profile and weight loss. This study aims to further investigate if removal of abdominal fat (major omentum) leads to beneficial metabolic effects.
Eligibility Criteria
Inclusion Criteria
Body mass index over 40 kg/m2
Body mass index over 35 kg/m2 with obesity associated co-morbidities such as type 2 diabetes and/or additional cardiovascular risk factors -
Exclusion Criteria
-
Data sourced from ClinicalTrials.gov (NCT01785134). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.