N/A
Completed N=26
Motor Cortex Plasticity and the Effect of Deep Intramuscular Needling Stimulation Therapy (DIMST) in Osteoarthritis Pain
Source: ClinicalTrials.gov NCT01855958 ↗Enrolled (actual)
26
Serious AEs
0.0%
Results posted
Sep 2015
Primary outcomePrimary: Pain Pressure Threshold (PPT) After Intervention.. — 8.82; 6.66 Kgf / cm2
Summary
The aim of this study is to evaluate the cortical excitability in pain of knee osteoarthritis (OA), as well as the effect of one session of a kind of electroacupuncture (deep needling intramuscular stimulation therapy - DIMST) in this pain and the cortical excitability after the intervention.
The hypothesis is that cortical excitability is altered in this condition, confirming the findings already described in other chronic pain conditions. The investigators also believe that a session DIMST can reduce pain and alter cortical excitability, restoring its previous activity will occur from chronic pain.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Pressure Threshold (PPT) After Intervention.. |
8.82; 6.66 | — |
| PRIMARY Motor Evoked Potential (MEP) After Intervention. |
1.14; 1.12 | — |
| PRIMARY Conditioned Pain Modulation (CPM) After Intervention. |
12.62; 9.15 | — |
| SECONDARY Intracortical Inhibition (ICI) After Intervention. |
0.75; 0.57 | — |
| SECONDARY Pain Intensity After Intervention. |
0.88; 3.36 | — |
| SECONDARY Intracortical Facilitation (ICF) After Intervention. |
1.20; 0.78 | — |
| SECONDARY Cortical Silent Period (CSP) After Intervention. |
50.93; 48.92 | — |
Eligibility Criteria
Inclusion Criteria
- Women with over 18 years old, with chronic pain because of primary osteoarthritis of the knee.
- Pain stable for at least three months. Score greater than or equal to 3 cm (0 cm = "no pain" and "worst possible pain" = 10cm) on VAS for pain perception at baseline.
- No contraindications to electro acupuncture or transcranial magnetic stimulation.
- Naive in acupuncture treatment.
Exclusion Criteria
- Clinically significant or unstable disorder, medical or psychiatric.
- Presence of neurological or rheumatic comorbidity.
- Pregnancy.
- Having performed surgery in the knee to be treated in the last 6 months, or be planning surgery for the next semester.
- Having performed with corticosteroid infiltration in the last six weeks or are using this.
- Having performed with hyaluronic acid infiltration.
Data sourced from ClinicalTrials.gov (NCT01855958). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.