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N/A N=40 Randomized Double-blind Treatment

Visual Performance Investigation of Two Toric Soft Contact Lenses

Refractive Error · Astigmatism · Myopia · Hyperopia

Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Oct 2014
Primary outcome: Primary: Mean Ocular Coma Score at 5mm Pupil at Day 30 — 0.16; 0.24 micrometers

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Lotrafilcon B toric contact lens (Device); Comfilcon A toric contact lens (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Alcon Research
Primary completion
Oct 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Ocular Coma Score at 5mm Pupil at Day 30
0.16; 0.24

Summary

The purpose of this study is to compare the amount of coma as measured by aberrometry induced by two silicone hydrogel toric lenses in astigmatic participants.

Eligibility Criteria

Inclusion Criteria

  • Sign informed consent;
  • Wears toric soft contact lenses;
  • Can be successfully fit with study lenses within the power ranges available;
  • Has cylinder of ≥ -0.75 diopter in both eyes;
  • Has correctable vision of at least 0.1 (logMAR) or better in each eye at distance with both study lenses;
  • Willing and able to wear study lenses on a daily wear basis for at least 5 days a week, minimum 8 hours per day, and attend all study visits;
  • Other protocol-defined inclusion criteria may apply.

Exclusion Criteria

  • Any ocular condition that would contraindicate contact lens wear;
  • Use of medications for which contact lens wear could be contraindicated;
  • Monocular (only 1 eye with functional vision) or fit with 1 lens;
  • History of herpetic keratitis, ocular surgery, or irregular cornea;
  • Known sensitivity to the diagnostic pharmaceuticals to be used in the study;
  • Requires presbyopic correction;
  • Use of rewetting/lubricating eye-drops more than twice a day;
  • Other protocol-defined exclusion criteria may apply.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01858701). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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