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N/A Completed N=525 Randomized Quadruple-blind Prevention

Xylitol for Caries Prevention in Inner-City Children

Source: ClinicalTrials.gov NCT01901250 ↗
Enrolled (actual)
525
Serious AEs
0.0%
Results posted
Aug 2014
Primary outcomePrimary: Change in the Number of Decayed or Filled Permanent Teeth (DFT) From Baseline (Beginning of Kindergarten) to the Middle of 2nd Grade — 0.38; 0.48 Number of surfaces — p=0.25

Summary

The purposes of this study is to determine whether xylitol use in kindergarten school children in addition to oral health education, provision of tooth brush and fluoride paste, fluoride varnish and sealant treatment will reduce decay in the first permanent molars and other permanent teeth.

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in the Number of Decayed or Filled Permanent Teeth (DFT) From Baseline (Beginning of Kindergarten) to the Middle of 2nd Grade
0.38; 0.48 0.25

Eligibility Criteria

Inclusion Criteria

  • attending kindergarten in one of the participating schools
  • must have parental permission

Exclusion Criteria

  • children with severe stomach illness (ex. Crohn's disease, ulcerative colitis, Celiac disease, irritable bowel syndrome, etc.)
  • children with strict dietary restriction (ex. Diabetes)
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01901250). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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