How many clinical trials are tracked for Dental Caries?

75 trials are tracked, 4 with published results.

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Dental Caries

11 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Dental Caries

75 trials tracked for Dental Caries: 14 in phase 3 or 4 and 4 with published results. The most-cited published study has 365 citations.

75Trials tracked

14Phase 3 & 4

0Recruiting

4With published results

Phase distribution

Phase 4 3 Phase 3 11 Phase 2 12 Phase 1 2 Other / NA 47

Phase 4 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study Completed · 365 cited
Phase 3 Prevention of Adult Caries Study (PACS) Completed · 33 cited
Phase 4 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Completed · 23 cited
Phase 3 Preventing and Arresting Dental Root Surface Caries in Community-dwelling Older Adults Completed · 23 cited
Phase 4 Enamel Remineralization Potential of Dentifrices in Situ Completed
Phase 3 Reducing Bacteria That Cause Tooth Decay Completed

Show 44 more trials

Phase 3 Stopping Cavities Study: Diammine Silver Fluoride Completed
Phase 3 Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique Completed
Phase 3 Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART Completed
Phase 3 Fluoride Varnish Randomized Clinical Trial Completed
Phase 3 Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries Completed
Phase 3 Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes Completed
Phase 3 Effect of pH and Fluoride Concentration of Dentifrices on Caries Control Completed
Phase 3 A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model Completed
Phase 2 Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries Completed
Phase 2 A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects Completed
Phase 2 A Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Dental Strip Application Completed
Phase 2 A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects Completed
Phase 2 Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse Completed
Phase 2 MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial Completed
Phase 2 Self Assembling Peptide P11-4 in Patients With Early Occlusal Carious Lesions Completed
Phase 2 Pharmacokinetics of Advantage Anti-Caries Varnish Completed
Phase 2 Effect of CPP-ACP Paste on Dental Caries in Primary Teeth Completed
Phase 2 Pharmacokinetics of Advantage Arrest Completed
Phase 2 Pharmacokinetics of Advantage Arrest in Children Completed
Phase 2 Efficacy Of A PVP-I Fluoride Varnish Completed
Phase 1 Safety Evaluation of Advantage Anti-Caries Varnish Completed
Phase 1 Effect of Calcium Glycerophosphate (CaGP) - Fluoride Dentifrice on Dental Biofilm pH Completed
N/A Validation of Near-infrared Light Transillumination for Interproximal Enamel Caries Detection Completed
N/A Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride Completed
N/A Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite Completed
N/A Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients Completed
N/A Ecological Effect of Arginine Dentifrice on Oral Microbiota Completed
N/A Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study Completed
N/A Composites and Urinary Bisphenol-A Study Completed
N/A Providers Against Cavities in Children's Teeth Completed
N/A Healthy Hydration Pilot in Elementary Schools Completed
N/A A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images Completed
N/A Evaluation of Oral Hygiene Products in an In Situ Caries Model Completed
N/A Assessment of Caries Diagnosis and Caries Treatment in Dental PBRN Japan Completed
N/A Clinical Evaluation of a Bulk Fill Resin Composite Completed
N/A Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant Completed
N/A European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth Completed
N/A Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study Completed
N/A A Comparative Study of Papacarie® and the Conventional Method for Dental Caries Treatment Completed
N/A Clinical Performance of Chairside CAD/CAM Restorations Completed
N/A Clinical Performance of Incremental and Bulk Fill Composites in Class II Restorations Completed
N/A Older Adult Effectiveness of 2 Treatments Completed
N/A In Vivo Comparison of Salivary Fluoride Levels Following the Application of Different 5% NaF Varnishes Completed
N/A Clinical Investigation of the F-Composite 2 System in Direct Filling Therapy Completed

Showing the 50 most-cited and recently-updated of 75 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

Questions about Dental Caries

Does drinking fluoridated water from U.S. systems help prevent dental caries?

Yes, fluoridated water helps prevent cavities by strengthening enamel and reducing acid damage, though many U.S. systems face challenges in maintaining optimal levels.

Full answer →

Can using an 8% arginine toothpaste reduce dental caries in teenagers?

Using an 8% arginine toothpaste significantly reduces dental caries in teenagers aged 10 to 14 by lowering decay scores compared to standard fluoride toothpaste.

Full answer →