N/A
N=67
Building Employment Skills Through Therapy for Veterans
Schizophrenia · Schizoaffective Disorder
Bottom Line
View on ClinicalTrials.gov: NCT01992913 ↗Enrolled (actual)
67
Serious AEs
31.3%
Results posted
Jan 2025
Primary outcome: Primary: Workforce Participation Measure - Total Number of Jobs Attained — 0; 0; 0.95; 0.43 Number of jobs attained
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- integrated Cognitive Behavioral Therapy (Behavioral); Usual Care (Other); Computerized cognitive remediation (CCR) (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Sep 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Workforce Participation Measure - Total Number of Jobs Attained |
0; 0; 0.95; 0.43 | — |
| PRIMARY Overall Job Attainment Proportion |
16; 20; 21; 10 | <.05 sig |
| PRIMARY Job Participant Composite-hours Worked |
96.5; 25.3; 109.3; 27.0; 110.8; 77.3 | <0.33 |
| SECONDARY Work Behavior Inventory |
5.0; 4.0 | — |
| SECONDARY Specific Levels of Functioning (SLOF) |
128.0; 123.0; 125.3; 127.8; 127.8; 127.2 | <0.19 |
Summary
Schizophrenia/Schizoaffective Disorder is associated with serious problems with cognitive skills, social skills, and functional skills (like employment). There is a new form of cognitive behavioral therapy called integrated cognitive behavioral therapy (iCBT) that specifically addresses the cognitive, social, and functional deficits of schizophrenia/schizoaffective disorder. This study compared iCBT to the usual care (UC) that Veteran's receive. The investigators compared iCBT to UC in subjects with schizophrenia/schizoaffective disorder who are enrolled in a Supported Employment (SE) program, and evaluate whether iCBT is more helpful in improving job attainment, and other areas of functioning, both right after treatment, and 6 months after the end of treatment.
Eligibility Criteria
Inclusion Criteria
- Diagnosis of DSM-IV schizophrenia or schizoaffective disorder (SCID)
- Severe/extreme functional disability [World Health Organization Disability Assessment Scale (WHODAS) score > 50]
- Clinical stability (as per primary mental health provider)
- Receiving treatment at the Veterans Administration
- Minimal engagement in psychiatric rehabilitation services (just psychiatrist and therapist/case management in the last 6 months)
- Eligible for and willing to be enrolled in Supported Employment program
- Age 18 to 65
- Proficient in English
- Able to give informed consent
Exclusion Criteria
- Neurologic disease or damage that would make the diagnosis of schizophrenia questionable
- Current opioid or stimulant dependence (SCID)
- Not appropriate due to safety concerns (based on risk assessment)
Data sourced from ClinicalTrials.gov (NCT01992913). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.