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N/A N=30 Randomized Single-blind Other

BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens

Myopia

Enrolled (actual)
30
Serious AEs
0.0%
Results posted
Apr 2016
Primary outcome: Primary: Ocular Health - Corneal Staining — 38; 35; 18; 20 Eyes

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Bioclean First Care EX / comfilcon A (Other); Aosept Clearcare / comfilcon A (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
CooperVision, Inc.
Primary completion
Aug 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Ocular Health - Corneal Staining
38; 35; 18; 20; 4; 5
PRIMARY
Ocular Health - Conjunctival Redness
40; 40; 20; 20; 0; 0
PRIMARY
Ocular Health - Limbal Redness
49; 47; 11; 12; 0; 1
PRIMARY
Ocular Health - Papillary Conjunctivitis
52; 51; 7; 8; 1; 1
SECONDARY
Stinging Sensation Right After Insertion (Subjective Rating)
9.5; 9.4
SECONDARY
Burning Sensation Right After Insertion (Subjective Rating)
9.5; 9.4

Summary

To determine if patients are unreactive to the lens care solution / Biofinity combination.

Eligibility Criteria

Inclusion Criteria

  • Is over 18 years of age (inclusive)
  • Has had a self-reported visual exam in the last two years
  • Is currently an adapted spherical soft CL wearer
  • Has a CL spherical prescription between - 0.25 and - 12.00 (inclusive)
  • Has less than 1.00D spectacle cylinder in each eye.
  • Is correctable to a visual acuity of 20/20 or better in both eyes
  • Has clear corneas and no active ocular disease
  • Has read, understood and signed the information consent letter.
  • Is willing to comply with the wear schedule (at least 40 hrs per week)
  • Is willing to comply with the visit schedule

Exclusion Criteria

  • Has never worn contact lenses before.
  • Currently wears rigid gas permeable contact lenses.
  • Has a history of not achieving comfortable CL wear (5 days per week; > 8 hours/day)
  • Has a CL prescription outside the range of - 0.25 to -12.00D
  • Has a spectacle cylinder greater than -0.75D of cylinder in either eye.
  • Has best corrected spectacle distance vision worse than 20/20 in either eye.
  • Has any systemic disease affecting ocular health.
  • Is using any systemic or topical medications that will affect ocular health.
  • Has any ocular pathology or severe insufficiency of lacrimal secretion
  • Has persistent, clinically significant corneal or conjunctival staining
  • Has active neovascularization or any central corneal scars.
  • Is aphakic.
  • Is pregnant or lactating.
  • Has undergone corneal refractive surgery.
  • Is participating in any other type of eye related clinical or research study.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02196766). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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