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N/A N=36 Randomized Double-blind Treatment

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

Thyroid Neoplasms · Goiter, Nodular · Thyroid Nodule · Graves' Disease · Hyperparathyroidism

Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Feb 2018
Primary outcome: Primary: Intraoperative Fentanyl Administration — 187.5; 185.7; 144.2; 156.3 mcg

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Superficial Cervical Plexus Block (Procedure); Local Wound Infiltration (Procedure); 0.9% saline (Drug); Marcaine (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Chicago
Primary completion
Feb 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Intraoperative Fentanyl Administration
187.5; 185.7; 144.2; 156.3
SECONDARY
Post Operative Pain
3; 2.8; 4.4; 2.9; 1.4; 3.4
SECONDARY
Post Operative Nausea Score
1.3; 1.0; 1.4; 1.4; 1.7; 1.2
SECONDARY
Total Pain Medication Utilization
0.56; 0.71; 0.84; 0.79

Summary

We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy. We hypothesize there is equivalent pain control between bilateral superficial cervical plexus block and local wound infiltration when used in conjunction with a general anesthetic.

Eligibility Criteria

Inclusion Criteria

  • Patient ≥ 18 years old
  • Surgical indication for parathyroidectomy or thyroidectomy

Exclusion Criteria

  • Patients < 18 years old
  • Patient with history of chronic opioid use
  • Patient with chronic pain syndromes
  • Patient with allergy to marcaine
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02205801). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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