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Thyroid Nodules

Part of Head and Neck Cancer

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Thyroid Nodules

8 trials tracked for Thyroid Nodules.

8Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
  1. N/A Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules Completed
  2. N/A Diagnostic Accuracy of Shear-Wave Elastography for the Preoperative Risk Stratification of Follicular Lesions of the Thyroid Completed
  3. N/A Efficacy of a Spirulina Supplement for Amelioration of Benign ThYroid Nodules Completed
  4. N/A AIM2: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid Completed
  5. N/A Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy Completed
  6. N/A The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer Completed
Show 2 more trials
  1. N/A AIM1: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid Completed
  2. N/A Reciprocating Medical Devices - a Study of a New Safety Device Completed

Showing the 8 most-cited and recently-updated of 8 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Head and Neck Cancer

Related studies from across the Head and Neck Cancer family.

Case report review highlights suspicion of breast cancer metastasis to thyroid in a 54-year-old woman
Orthopedics & Sports Medicine Sys. Review
Case report review highlights suspicion of breast cancer metastasis to thyroid in a 54-year-old woman Breast cancer can spread to the thyroid gland in rare cases
This case report review describes a 54-year-old woman with a history of breast cancer who developed metastasis to the thyroid. The authors n…
A single case report shows a 54-year-old woman survived after breast cancer spread to her thyroid, highlighting the need for careful diagnos…
Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer
Allergy & Immunology Sys. Review
Case report and review: IVIg and efgartigimod in Guillain-Barré with Graves disease and thyroid cancer Doctors treat a rare relapse of Guillain-Barré syndrome with new immune therapies
This case report and literature review describes a 33-year-old man with Guillain-Barré syndrome, Graves disease, and papillary thyroid carci…
A 33-year-old man with Guillain-Barré syndrome found relief after doctors treated his underlying thyroid cancer and used new immune therapie…
Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns
Diabetes & Endocrinology Sys. Review
Review of 32 cases of thyroid hemiagenesis with carcinoma highlights surgical and diagnostic patterns Doctors found rare thyroid cancer cases in patients with one missing half of their gland
This review and case series of 32 patients with thyroid hemiagenesis complicated by thyroid carcinoma synthesized diagnostic and treatment p…
A review of thirty-two patients shows that having half a thyroid gland does not stop cancer from forming. Most cases were treated with surge…
Machine learning model predicts central lymph node metastasis in papillary thyroid carcinoma
Diabetes & Endocrinology Cohort
Machine learning model predicts central lymph node metastasis in papillary thyroid carcinoma New AI tool predicts hidden cancer spread in early thyroid cases
This retrospective cohort study of 710 patients with clinically node-negative T1–T2 papillary thyroid carcinoma developed an interpretable m…
A smart new computer model can spot hidden cancer spread in early thyroid cases, helping surgeons decide exactly what to remove during opera…
Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions
Oncology Sys. Review
Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions Rare Thyroid Cancer Has Unique Genetic Signature
This case series with literature review describes four pathologically confirmed cases of clear cell variant of papillary thyroid carcinoma d…
A rare thyroid cancer type may have a specific genetic cause that doctors can now look for.
Autopsy study finds 55% thyroid nodular disease prevalence in Mexico City hospital patients
Neurology Cohort
Autopsy study finds 55% thyroid nodular disease prevalence in Mexico City hospital patients Autopsy study finds high thyroid nodule rates in Mexico City, no link to salt iodination
A retrospective cohort study of 487 autopsies from a third-level hospital in Mexico City found a thyroid nodular disease prevalence of 55% a…
Autopsies in Mexico City reveal thyroid nodules are very common, yet changing salt iodination rules did not increase their rates.
Deep learning model using preoperative CT predicts lymph node metastasis in papillary thyroid carcinoma
Oncology Cohort
Deep learning model using preoperative CT predicts lymph node metastasis in papillary thyroid carcinoma Can a new AI model help thyroid cancer patients avoid unnecessary surgery?
A retrospective cohort study of 1560 PTC patients developed and validated ThyLNT, a Transformer-based 2.5D deep learning model using preoper…
A new AI model predicts lymph node spread in thyroid cancer better than standard scans, potentially sparing patients from unnecessary surger…
TyG-BMI index shows positive association with papillary thyroid carcinoma odds in Chinese cohort
Diabetes & Endocrinology Cohort
TyG-BMI index shows positive association with papillary thyroid carcinoma odds in Chinese cohort Study finds link between metabolic index and thyroid cancer risk in Chinese patients
A retrospective cohort study of 538 Chinese individuals with thyroid nodules or papillary thyroid carcinoma found the triglyceride-glucose-B…
Higher TyG-BMI scores linked to greater odds of papillary thyroid cancer in a Chinese study, with risk rising as the index score increased.
Machine learning algorithm predicts skip metastasis in papillary thyroid cancer in retrospective cohort
Oncology Cohort
Machine learning algorithm predicts skip metastasis in papillary thyroid cancer in retrospective cohort Can a computer help spot tricky thyroid cancer spread?
A retrospective, single-center cohort study of 361 patients undergoing thyroidectomy with lymph node dissections developed a machine learnin…
A computer program can spot tricky thyroid cancer spread that jumps over nearby nodes, helping surgeons plan more effective operations befor…

Questions about Thyroid Nodules

Is elevated weight linked to having high-risk thyroid nodules in a retrospective study?

A retrospective study found that higher body weight is linked to having high-risk thyroid nodules, alongside other factors like sedentary time and poor sleep.

Full answer →
How do TIRADS and Bethesda systems predict thyroid malignancy in patients with thyroid nodules?

TIRADS ultrasound scores and Bethesda cytology results work together to estimate cancer risk, with higher scores in either system indicating a greater chance of malignancy.

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Can BRAFV600E mutation testing help diagnose high-suspicion thyroid nodules with non-malignant cytology?

BRAFV600E mutation testing can help identify hidden cancers in thyroid nodules that look dangerous on ultrasound but test benign on standard cell samples.

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Do sedentary time and insomnia increase the risk of high-risk thyroid nodules?

Research indicates that sedentary time and insomnia are linked to a higher risk of developing high-risk thyroid nodules, while family history and neck swelling remain key clinical warning signs.

Full answer →