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N/A N=81 Randomized Supportive Care

Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients

Postoperative Complications · Obesity · Gynecologic Neoplasms

Enrolled (actual)
81
Serious AEs
29.6%
Results posted
Jul 2020
Primary outcome: Primary: Number of Participants Who Experience Wound Complications (Wound Dehiscence or Infection) — 25; 33; 12; 9 Participants — p=0.27

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Standard Wound Closure (Procedure); Prevena™ Incision Management System (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Masonic Cancer Center, University of Minnesota
Primary completion
Jun 2020

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants Who Experience Wound Complications (Wound Dehiscence or Infection)
25; 33; 12; 9 0.27
SECONDARY
Time From Surgery to Starting Adjuvant Therapy Among Those With Confirmed Malignancies
37; 28

Summary

The purpose of the study is to test whether the use of a new wound closure technique can decrease the rates of wound complications in obese cancer patients.

Eligibility Criteria

Inclusion Criteria

  • Known or suspected gynecologic or other abdominal malignancy (such as colorectal, liver, pancreatic, kidney and stomach) for which laparotomy is planned
  • Obese - defined as a Body Mass Index (BMI) ≥ 35 kg/m2 as calculated in the Epic computer record

Exclusion Criteria

  • Known true tape allergy
  • Sensitivity to silver
  • History of intolerance to Negative Pressure Wound Therapy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02309944). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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