Meta-analysis shows lower prosthetic joint infection odds with cephalosporins versus non-cephalosporin prophylaxis in primary arthroplasty
Cephalosporins lower prosthetic joint infection risk in primary hip and knee replacements
This systematic review and meta-analysis evaluated single-agent cephalosporin prophylaxis against non-cephalosporin antibiotics in adults un…
A large review of over 200,000 surgeries found lower infection rates when using cephalosporins for prevention.
Dual antibiotic-loaded bone cement reduces surgical site infection risk in cemented hip arthroplasty patients compared to single cement
Dual antibiotic cement cuts infection risk for hip surgery patients
This systematic review and meta-analysis evaluated dual antibiotic-loaded bone cement versus single antibiotic-loaded bone cement in patient…
A large analysis shows dual antibiotic-loaded bone cement significantly lowers surgical site infection risk compared to single antibiotic ve…
Meta-analysis: Postoperative oral antibiotics reduce cellulitis after cesarean in obese women
Adding two antibiotics may lower cellulitis risk for obese women having C-sections
This systematic review and meta-analysis of 1144 obese women undergoing cesarean delivery found that adding postoperative oral cephalexin an…
A large review found adding oral cephalexin and metronidazole to standard care significantly reduced cellulitis in obese women after C-secti…
Diabetes and age increase surgical site infection risk in spinal surgery patients based on a multicenter cohort
Researchers find diabetes and age raise infection risk after spinal surgery
This retrospective cohort study analyzed 1,049 patients who underwent spinal surgeries at multiple centers.
Spinal surgery patients with diabetes or older age face significantly higher risks of surgical site infections during recovery.
Translational review of oxidative stress interventions in experimental ischemia-reperfusion injury models
Saving Tissue After Surgery: A New Plan to Stop Damage
This translational mechanistic synthesis review evaluates interventions targeting the oxidative stress–inflammation–microvascular dysfunctio…
Stopping damage when blood returns after surgery helps patients needing skin or tissue transfers for reconstruction, research shows.
Narrative review explores metformin and trimetazidine in cardiovascular conditions
The Hidden Cell Death Process Quietly Driving Heart Disease
This narrative review examines the roles of metformin and trimetazidine in cardiovascular diseases, atherosclerosis, vascular calcification,…
A specific type of cell death driven by iron and fat damage plays a key role in multiple heart conditions, including heart failure and ather…
Natural and synthetic compounds suppress inflammasome activation in NLRP3-driven pathologies
Your body has a built-in alarm system. It wakes up when you get a sore throat or a fever. But sometimes, this alarm gets stuck in the "on" position. That stuck alarm causes chronic pain and swelling. Scientists are finally learning how to turn it off
This systematic review examined molecular mechanisms involving natural compounds like oridonin and pristimerin, alongside synthetic inhibito…
A hidden protein key inside your cells triggers the stuck alarm that causes chronic pain and swelling, and scientists now know how to stop i…
CRP dynamics after surgery may help detect surgical site infections in single-center analysis
A Common Blood Test Can Catch Hidden Surgical Infections Days Earlier
A single-center retrospective cohort analysis of 127 surgical patients found that CRP level >106 mg/L on postoperative day 3 was associated …
A common inflammation blood test, taken on the third day after surgery, predicted hidden surgical site infections better than waiting for sy…
Emergent arterial embolization for delayed GDA bleeding after major abdominal surgery
A Lifesaving Shift for a Rare Surgical Emergency
A retrospective cohort of 6 patients with delayed massive gastroduodenal artery bleeding after gastrectomy or pancreaticoduodenectomy found …
For a rare but deadly surgical complication, a minimally invasive technique is emerging as a fast and effective lifesaver.
Review of interferon regulatory factors in ischemia-reperfusion injury across multiple organ systems
Review suggests targeting IRFs may help prevent organ injury from blood flow changes
This review examines regulatory mechanisms and advances regarding interferon regulatory factors (IRFs) in ischemia-reperfusion injury (IRI) …
Targeting interferon regulatory factors offers a new way to prevent severe organ damage when blood flow returns to tissues after a disruptio…
Single Preoperative Antibiotic Dose vs Week-Long Postoperative Course for SSI Prevention in TE Breast Reconstruction
Is one antibiotic dose enough to prevent infection after breast reconstruction?
A multi-institutional RCT of 214 women undergoing immediate tissue expander breast reconstruction compared a single preoperative antibiotic …
A single antibiotic dose before breast reconstruction led to a 17% infection rate, compared to 11% with a week of pills, but the study didn'…
Systematic review links immune cell metabolic remodeling to outcomes in liver transplant recipients
Could immune cell energy shifts hold the key to better liver transplant survival?
A systematic review synthesizes evidence on immunometabolic remodeling in liver transplant recipients.
Immune cell energy shifts after liver transplants determine rejection, injury, and tolerance, improving long-term survival, a new analysis f…
All Postoperative Complications Articles
- Meta-analysis shows lower prosthetic joint infection odds with cephalosporins versus non-cephalosporin prophylaxis in primary arthroplasty
- Dual antibiotic-loaded bone cement reduces surgical site infection risk in cemented hip arthroplasty patients compared to single cement
- Meta-analysis: Postoperative oral antibiotics reduce cellulitis after cesarean in obese women
- Diabetes and age increase surgical site infection risk in spinal surgery patients based on a multicenter cohort
- Translational review of oxidative stress interventions in experimental ischemia-reperfusion injury models
- Narrative review explores metformin and trimetazidine in cardiovascular conditions
- Natural and synthetic compounds suppress inflammasome activation in NLRP3-driven pathologies
- CRP dynamics after surgery may help detect surgical site infections in single-center analysis
- Emergent arterial embolization for delayed GDA bleeding after major abdominal surgery
- Single Preoperative Antibiotic Dose vs Week-Long Postoperative Course for SSI Prevention in TE Breast Reconstruction
- Review of interferon regulatory factors in ischemia-reperfusion injury across multiple organ systems
- Systematic review links immune cell metabolic remodeling to outcomes in liver transplant recipients
- Qualitative analysis explores LARS self-management experiences via online peer support app
- Pyloroplasty during minimally invasive esophagectomy linked to fewer short-term complications
- Short-course antibiotics after appendectomy for complicated appendicitis show similar infection risk to long-course therapy
- Review analyzes PANoptosis mechanisms and potential treatments for ischemia-reperfusion injury