N/A
Completed N=160
Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction
Source: ClinicalTrials.gov NCT02454127 ↗Enrolled (actual)
160
Serious AEs
0.0%
Results posted
Oct 2016
Primary outcomePrimary: Weight Loss — -2.1; -3.2; -3.0; -3.3 kg
Summary
A single-center randomized trial at an academic medical center in Boston, Mass, of overweight or obese adults with known hypertension, dyslipidemia, or fasting hyperglycemia. Participants were enrolled starting July 18, 2000, and randomized to 4 popular diet groups until January 24, 2002.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Weight Loss |
-2.1; -3.2; -3.0; -3.3 | — |
| SECONDARY Total Cholesterol |
-4.3; -10.1; -8.2; -10.8 | — |
| SECONDARY LDL Cholesterol |
-7.1; -11.8; -9.3; -12.6 | — |
| SECONDARY HDL Cholesterol |
3.4; 3.3; 3.4; -0.5 | — |
| SECONDARY Triglycerides |
-1.2; 2.5; -12.7; 5.6 | — |
| SECONDARY Glucose |
1.4; -4.2; -4.7; -4.1 | — |
| SECONDARY Insulin |
-1.2; -5.4; -2.6; -3.0 | — |
| SECONDARY C-reactive Protein |
-0.70; -0.58; -0.58; -0.88 | — |
Eligibility Criteria
Inclusion Criteria
- BMI 27-42;
- At least one metabolic cardiac risk factor
Exclusion Criteria
- Age under 18 years;
- Insulin therapy;
- Unstable chronic illness;
- Unwilling to follow dietary advice
Data sourced from ClinicalTrials.gov (NCT02454127). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.