N/A
N=160
Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction
Obesity · Cardiovascular Disease · Metabolic Syndrome
Bottom Line
View on ClinicalTrials.gov: NCT02454127 ↗Enrolled (actual)
160
Serious AEs
0.0%
Results posted
Oct 2016
Primary outcome: Primary: Weight Loss — -2.1; -3.2; -3.0; -3.3 kg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Atkins Diet (Behavioral); Zone Diet (Behavioral); Weight Watchers Diet (Behavioral); Ornish Diet (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Tufts Medical Center
- Primary completion
- Jan 2003
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Weight Loss |
-2.1; -3.2; -3.0; -3.3 | — |
| SECONDARY Total Cholesterol |
-4.3; -10.1; -8.2; -10.8 | — |
| SECONDARY LDL Cholesterol |
-7.1; -11.8; -9.3; -12.6 | — |
| SECONDARY HDL Cholesterol |
3.4; 3.3; 3.4; -0.5 | — |
| SECONDARY Triglycerides |
-1.2; 2.5; -12.7; 5.6 | — |
| SECONDARY Glucose |
1.4; -4.2; -4.7; -4.1 | — |
| SECONDARY Insulin |
-1.2; -5.4; -2.6; -3.0 | — |
| SECONDARY C-reactive Protein |
-0.70; -0.58; -0.58; -0.88 | — |
Summary
A single-center randomized trial at an academic medical center in Boston, Mass, of overweight or obese adults with known hypertension, dyslipidemia, or fasting hyperglycemia. Participants were enrolled starting July 18, 2000, and randomized to 4 popular diet groups until January 24, 2002.
Eligibility Criteria
Inclusion Criteria
- BMI 27-42;
- At least one metabolic cardiac risk factor
Exclusion Criteria
- Age under 18 years;
- Insulin therapy;
- Unstable chronic illness;
- Unwilling to follow dietary advice
Data sourced from ClinicalTrials.gov (NCT02454127). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.