Phase 3 N=66 Randomized Quadruple-blind Treatment

Stopping Cavities Study: Diammine Silver Fluoride

Dental Caries

Bottom Line

View on ClinicalTrials.gov: NCT02536040 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2020

Primary outcome: Primary: Dental Caries Activity — .72; .05 Proportion of arrested caries lesions

Study Design & Population

Study type: Interventional
Phase: Phase 3
Interventions: 38% diammine silver fluoride (Drug); Water (Other)
Age: Pediatric · 0+ yrs
Sex: All
Sponsor: Advantage Dental Services, LLC
Primary completion: Jul 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Dental Caries Activity	.72; .05	—

Summary

This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.

Eligibility Criteria

Inclusion Criteria

Nyvad criteria 3
Active carious lesion

Exclusion Criteria

Allergy to silver
Stomatitis or oral ulcerative condition
Weight less than 15 kg

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02536040). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.