N/A
N=1,705
ED Lung Protective Ventilation to Reduce Complications
Mechanical Ventilation · Ventilator-associated Conditions · ARDS
Bottom Line
View on ClinicalTrials.gov: NCT02543554 ↗Enrolled (actual)
1,705
Serious AEs
0.0%
Results posted
Dec 2018
Primary outcome: Primary: Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department — 171; 38 participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- lung protective ventilation (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Washington University School of Medicine
- Primary completion
- Mar 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department |
171; 38 | — |
| SECONDARY Number of Patients That Die During the Hospitalization |
338; 105 | — |
Summary
Early mechanical ventilation, if delivered with injurious settings, can lead to pulmonary complications, such as acute respiratory distress syndrome (ARDS). Mechanical ventilation in the emergency department (ED) has been studied infrequently when compared to the intensive care unit; however, data suggests that ED-based mechanical ventilation has significant room for improvement and may also be a causative factor in ARDS incidence.
Eligibility Criteria
Inclusion Criteria
- mechanically ventilated via an endotracheal tube in the ED
Exclusion Criteria
- death in the ED,
- death or discontinuation of ventilation within 24 hours,
- chronic mechanical ventilation,
- ARDS while in the ED
- transfer to another hospital.
Data sourced from ClinicalTrials.gov (NCT02543554). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.