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Phase 4 Completed N=140 Randomized Treatment

A Randomized Clinical Trial Evaluating Negative Pressure Therapy to Decrease Vascular Groin Incision Complications

Chronic Wounds · Peripheral arterial disease · Aneurysm · Surgical Wound Dehiscence
Source: ClinicalTrials.gov NCT02581904 ↗
Enrolled (actual)
140
Serious AEs
2.1%
Results posted
Feb 2026
Primary outcomePrimary: Groin Wound Complication — 6; 19; 1 Participants
◆ Published Evidence
Established
96citations · ~12 / year
A randomized clinical trial evaluating negative pressure therapy to decrease vascular groin incision complications.
Journal of vascular surgery · 2018 · Open access · Likely link

Summary

The purpose of this study is to determine if the application of a negative pressure dressing intraoperatively (Prevena; KCI, Inc) to vascular groin incisions decreases the wound complication rate in high risk patients.

Linked Publications (3)

  • A randomized clinical trial evaluating negative pressure therapy to decrease vascular groin incision complications.
    Journal of vascular surgery · 2018 · 96 citations · Open access · Likely link
  • Prevention of infection in aortic or aortoiliac peripheral arterial reconstruction.
    The Cochrane database of systematic reviews · 2025 · 1 citation · Open access · Likely link
  • Prevention of infection in peripheral arterial reconstruction of the lower limb.
    The Cochrane database of systematic reviews · 2025 · 0 citations · Open access · Likely link

Outcome Measures

OutcomeResultp-value
PRIMARY
Groin Wound Complication
6; 19; 1
SECONDARY
Hospital Length of Stay
10.6; 10.6; 3.8
SECONDARY
Return to Operating Room
5; 11; 1
SECONDARY
Hospital Readmission
4; 10; 1
SECONDARY
Index Hospital Cost
29,2952; 30,678; 17,549

Eligibility Criteria

Inclusion Criteria

  • All patients undergoing a femoral incision during vascular reconstruction or repair will be considered for study

Exclusion Criteria

  • Emergency procedure
  • Unable to give informed consent
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02581904) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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