N/A
Completed N=38
Effects of Buprenorphine on Mood in Adults With a Range of Depressive Symptomatology
Source: ClinicalTrials.gov NCT02659787 ↗Enrolled (actual)
38
Serious AEs
0.0%
Results posted
May 2019
Primary outcomePrimary: Subjective Effects as Assessed by Score on "Feel Drug", "Feel High", "Like Drug", and "Want More" Subscales of the Drug Effects Questionnaire Subjective Response With and Without Buprenorphine — 21.03; 10.64; 23.09; 19.8 units on a scale
Summary
This study seeks to to study the effects of buprenorphine, a partial mu-opioid agonist, on depressed mood in a healthy young adults with a range of depressive symptomatology.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Subjective Effects as Assessed by Score on "Feel Drug", "Feel High", "Like Drug", and "Want More" Subscales of the Drug Effects Questionnaire Subjective Response With and Without Buprenorphine |
21.03; 10.64; 23.09; 19.8; 10.91; 5.74 | — |
Eligibility Criteria
Inclusion Criteria
- Healthy adult volunteers
- High school education
- Fluency in English
- BMI between 19 and 30
Exclusion Criteria
- Medical conditions contraindicating study participation
- Regularly medication use
- Current or past opioid abuse or dependence
- Current or past drug or alcohol dependence
- Psychiatric illness
- Women who are pregnant or nursing
Data sourced from ClinicalTrials.gov (NCT02659787). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.