N/A
Completed N=20
Protection Against Insulin Resistance in Obesity
Source: ClinicalTrials.gov NCT02717832 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
May 2022
Primary outcomePrimary: Insulin Sensitivity — 273; 817 nmol/kg FFM/min /(µU/mL Insulin)
Summary
The overall goal of this project is to identify factors that "protect" some obese adults from becoming insulin resistant. Identifying mechanisms that help protect some obese adults from developing insulin resistance could lead to novel, targeted therapeutic and/or preventative strategies for obese adults who are insulin resistant.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Insulin Sensitivity |
273; 817 | — |
| SECONDARY Resting Metabolic Rate |
1509; 1325 | — |
Eligibility Criteria
Inclusion Criteria
- Body mass index [BMI]: 30-40 kg/m2
- Age: 18-45 years
- All women must be pre-menopausal
- Non-exerciser: no regularly planned exercise/physical activity
Exclusion Criteria
- Weight instability ≥ ±3kg ≥ 6 months
- Medications known to affect lipid and/or glucose metabolism
- Pregnancy or actively breast feeding
Data sourced from ClinicalTrials.gov (NCT02717832). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.