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N/A N=62 Randomized Single-blind Supportive Care

Triggered Palliative Care for Advanced Dementia

Alzheimer Disease · Dementia

Enrolled (actual)
62
Serious AEs
0.0%
Results posted
Jan 2019
Primary outcome: Primary: Hospital / Emergency Visits Per 60 Days (no. of Events/Follow-up Days) — .68; .53 events per day — p=0.415

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Specialty Palliative Care (Behavioral)
Age
Older Adult · 65+ yrs
Sex
All
Sponsor
University of North Carolina, Chapel Hill
Primary completion
Oct 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Hospital / Emergency Visits Per 60 Days (no. of Events/Follow-up Days)
.68; .53 0.415
SECONDARY
Patient Comfort End of Life in Dementia (CAD-EOLD)
34.8; 34.0 0.521
SECONDARY
Caregiver Strain
2.3; 2.4 0.409
SECONDARY
Percent of Participants With Referral to Hospice or Outpatient Palliative Care From Discharge to 60 Days Follow-Up
25; 3 0.019 sig
SECONDARY
Percent of Participants With Physician Orders for Life Sustaining Treatment (POLST)
79; 30 <0.001 sig
SECONDARY
Number of Palliative Care Domains in Treatment Plan
7.6; 2.7 <0.001 sig
SECONDARY
Number of Participants With Burdensome Treatments
9; 8 0.516

Summary

The objective of this study is to generate preliminary data for a large multi-site randomized clinical trial of a model of palliative care consultation for patients with advanced dementia, and for their family caregivers.

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of dementia from Alzheimer's or other underlying cause
  • Global Deterioration Scale (GDS) Stage 5, 6 or 7
  • acute illness hospitalization

Exclusion Criteria

  • No English-speaking family decision-maker
  • Primary physician expects study to be too stressful for family caregiver
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02719938). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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