N/A N=60 Randomized Double-blind Treatment

Mindfulness Training in Healthy Older Veterans

Aging

Bottom Line

View on ClinicalTrials.gov: NCT02816723 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2020

Primary outcome: Primary: Geriatric Depression Scale Change Score — .89; 0.50 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Mindfulness-based Stress Reduction (Behavioral); Brain Health (Behavioral)
Age: Adult, Older Adult · 50+ yrs
Sex: All
Sponsor: VA Office of Research and Development
Primary completion: May 2019

Outcome Measures

Outcome	Result	p-value
PRIMARY Geriatric Depression Scale Change Score	.89; 0.50	—
PRIMARY State-Trait Anxiety Inventory (STAI) Change Score	.06; 2.75	—
SECONDARY Repeatable Battery for Neuropsychological Status (RBANS) Total Scaled Change Score	5.09; 5.38	—

Summary

Evidence shows the positive effects of Brain Health & Wellness classes in younger individuals. The proposed study investigates the usefulness of these classes in older Veterans aged 50-85. We hope to show that such classes can lead to improvements in both thinking skills as well as stress levels.

Eligibility Criteria

Inclusion Criteria

Subjects will be Veterans age 50-85

Exclusion Criteria

moderate or severe TBI
active alcohol or drug dependence or abuse by DSM-5 criteria (within previous 30 days)
positive urine drug screen for illicit substances
history of schizophrenia
ADHD
learning disability
dementia
Mild Cognitive Impairment and/or other psychiatric disturbances not including PTSD and/or depression
participants with a history of psychiatric hospitalization (last five years)
suicide attempt (last five years)
imminent risk for suicidal or homicidal behavior, or severe medical illness requiring treatment will be excluded
subjects with a history of neurological diagnosis, e.g.,:
brain tumor
clinical stroke
seizure
Mini-Mental Status Exam score below 19 (suggesting moderate/severe cognitive impairment, a contraindication to MBSR participation) will be excluded

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02816723). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.