N/A
N=346
Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer
Breast Cancer · Colorectal Cancer · Kidney Cancer · Lung Cancer · Prostate Cancer
Bottom Line
View on ClinicalTrials.gov: NCT02821793 ↗Enrolled (actual)
346
Serious AEs
—
Results posted
Jul 2025
Primary outcome: Primary: Priorities of Patients Receiving First Medical Treatment for Cancer at Treatment Initiation — 199; 93; 141; 80 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Consultation, evaluation questionnaire (Other); Geriatric consultation, evaluation questionnaire (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Institut Bergonié
- Primary completion
- Jun 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Priorities of Patients Receiving First Medical Treatment for Cancer at Treatment Initiation |
199; 93; 141; 80; 181; 67 | — |
| PRIMARY Priorities of Patients Receiving First Medical Treatment for Cancer 3 Months After Initiation of Treatment |
145; 85; 105; 72; 134; 66 | — |
| SECONDARY Expectations of Patients at Initiation of Treatment |
3; 0; 4; 0; 5; 0 | — |
| SECONDARY Expectations of Patients 3 Months After Initiation of Treatment |
1; 0; 5; 4; 9; 5 | — |
| SECONDARY Stability of Patients in Their Priorities at 3 Months |
137; 82; 74; 62; 119; 51 | — |
| SECONDARY 1-year Overall Survival |
77.5; 85.2 | — |
| SECONDARY Agreement Rate for Prioritization of Expectations Between Patients and Physicians |
174; 84; 123; 76; 128; 47 | — |
Summary
The main objective of study is to describe the priorities of elderly patients (70 years and over) undergoing a first medical treatment for cancer, at initiation of treatment and after 3 months of treatment. The main criterion is a prioritization of 4 items per patient from a list of 8 expectations regarding the objectives of their treatment: treatment efficacy, life expectancy, autonomy, daily activities, social activities, heaviness of treatment, toxicity, economics.
Eligibility Criteria
Inclusion Criteria
- Male or female:
- Age ≥ 70 years
- Aged 18-69 years (case population)
- ECOG / performance status 0-3 (WHO).
- First line of medical oncology treatment (chemotherapy, targeted therapy, hormone therapy, combination):
- Neo-adjuvant setting,
- Adjuvant setting: previous neo-adjuvant treatment is allowed,
- Metastatic setting: previous neo-adjuvant and/or adjuvant treatment are allowed,
- Solid tumors (breast, colorectal, kidney, lung, prostate, sarcoma, and ovarian) and lymphoma (indolent and aggressive).
- Life expectancy of more than 3 months.
- Patients potentially compliant with the rules of the follow-up study.
- Patients affiliated to a social security scheme.
- Patients who received clear information from the investigator on the study and had not refused to participate.
Exclusion Criteria
- Exclusive surgery treatment.
- Exclusive radiotherapy treatment or in combination with oncological medical treatment (concomitant radio-chemotherapy or radio-hormonotherapy).
- Previous first line of oncological medical treatment in the same indication as the one concerned by the inclusion:
- Neo-adjuvant setting: previous line(s) of neo-adjuvant medical treatment,
- Adjuvant setting: previous line(s) of adjuvant medical treatment,
- Metastatic setting: previous line(s) of metastatic medical treatment,
- Supportive care without specific medical treatment
- Previous or ongoing cancer under treatment at the time of inclusion.
- Patient already included in this study
- Patient who for psychological, psychiatric, social, family or geographical reasons could not be regularly monitored according to the criteria of the study; patient private of liberty or under guardianship.
Data sourced from ClinicalTrials.gov (NCT02821793). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.