N/A
Completed N=20
Remediation of Auditory Recognition in Schizophrenia With tDCS
Source: ClinicalTrials.gov NCT02869334 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Jul 2021
Primary outcomePrimary: Auditory Tone Matching Task — -4.3; 4.8 %correct, different trials
Summary
The purpose of this study is to determine whether transcranial direct current stimulation (tDCS), when combined with different forms of computer based training, improves the ability to discriminate small differences between sounds in people diagnosed with schizophrenia or schizoaffective disorder.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Auditory Tone Matching Task |
-4.3; 4.8 | — |
| SECONDARY Auditory Emotion Recognition (AER) Task |
-3.0; 5.1 | — |
| SECONDARY ER-40 |
-5.0; -1.3 | — |
| SECONDARY The Awareness of Social Inference Test (TASIT) |
10; 0 | — |
| SECONDARY Auditory Mismatch Negativity (MMN) |
-1.47; -.98 | — |
Eligibility Criteria
Inclusion Criteria
- Age 18-55
- Primary diagnosis of Schizophrenia or schizoaffective disorder
- English fluency
- Willing/capable to provide informed consent
- Auditory tone matching deficits
- Receiving stable doses of antipsychotic medication(s) for at least 2 weeks
- IQ>75
Exclusion Criteria
- Serious neurological disorder or medical condition/ treatment known to affect the brain. Neurological Disorder that affects the central nervous system (CNS), such as epilepsy, neurodegenerative disorders, movement disorders and sensory disorders.
- Current or past history (within the last 6 months) of substance abuse or dependence (excluding nicotine)
- Pregnancy or breastfeeding
- Taking anticholinergic medication (e.g. Cogentin, Thorazine, Clozaril, thioridazine)
Data sourced from ClinicalTrials.gov (NCT02869334). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.