N/A
N=60
The Effectiveness and Mechanism Study of Auricular Needling in Treating Cancer Induced Anorexia
Anorexia Nervosa · Cancer
Bottom Line
View on ClinicalTrials.gov: NCT02887586 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Jan 2024
Primary outcome: Primary: Simple Appetite Questionnaire — 8.7; 9.57; 11.26; 9.93 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- auricular needling (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
- Primary completion
- Dec 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Simple Appetite Questionnaire |
8.7; 9.57; 11.26; 9.93; 13.19; 9.50 | — |
| PRIMARY Symptom Based Anorexia Assessment |
8.70; 9.57; 11.26; 9.93; 13.19; 9.5 | — |
| SECONDARY Appetite Improvement |
6.56; 5.39; 4.56; 5.36; 3.59; 5.29 | — |
| SECONDARY Weight |
56.89; 58.47; 57.32; 58.30; 58.05; 57.86 | — |
| SECONDARY Acupuncture Treating Expectation Questionnaire |
12.26; 10.00; 13.74; 9.64; 14.30; 9.04 | — |
Summary
Controlling of cancer induced anorexia is highly demanded by advanced cancer patients. It plays an important role in improving the quality of life among advanced cancer patients. Through a randomized controlled single blinded clinical research, we will observe the differences of appetite, food intake amount, weight and KPS between the auricular needling treating group and control group before and after the treatment. Based on the results of the research, we can prove the clinical effectiveness of auricular needling in treating cancer induced anorexia and possible mechanism of the method.
Eligibility Criteria
Inclusion Criteria
- Histologically confirmed diagnosis of malignant cancer of stage III or IV
- Meet the diagnosis criteria of cancer induced anorexia
- Karnofsky performance status(KPS) score≥ 60
- Expected survival time≥3 months
- Willing to give informed consent
- Able to comply with trial protocol
Exclusion Criteria
- have blood routine, hepatic and renal disfunction,which is over 2 times of the normal value
- obvious eating disorder, intestinal obstruction, poor controlled heart disease and diabetes
- who are receiving progesterone, glucocorticoid or other hormone Therapy
- those who are participating in other trials.
- pregnant women, nursing mother or psychotic patients
Data sourced from ClinicalTrials.gov (NCT02887586). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.