N/A
Completed N=183
Empowered With Movement to Prevent Obesity and Weight Regain
Source: ClinicalTrials.gov NCT02923674 ↗Enrolled (actual)
183
Serious AEs
10.4%
Results posted
Mar 2022
Primary outcomePrimary: Body Weight — 94.7; 91.6; 95.1 kg
Summary
This study will help determine the appropriate type, amount and intensity of physical activity most beneficial for preventing weight regain after weight loss in older adults.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Body Weight |
89.8; 87.2; 88.7 | — |
Eligibility Criteria
Inclusion Criteria
- 65-85 years
- BMI=30-45 kg/m2
- Weight stable-no loss or gain (±5%) in past 6 mo
- Sedentary
- No contraindication for safe and optimal participation in exercise training
- Approved for participation by Medical Director
- Willing to provide informed consent
- Agree to all study procedures and assessments
- Able to provide own transportation to study visits and intervention
Exclusion Criteria
- Dependent on cane or walker
- Reported unintentional or intentional weight loss or gain of >5% in past 6 mo Participation in regular resistance training and/or > 20 mins/day of aerobic exercise in past 6 months
- Cognitive impairment (MoCA score 160/90 mmHg);
- Current or recent past (within 1 year) severe symptomatic heart disease, uncontrolled angina, stroke, chronic respiratory disease other than asthma or COPD, any disease requiring oxygen use, neurological or hematological disease; cancer requiring treatment in past year, except non-melanoma skin cancers
- Serious conduction disorder, new Q waves or ST-segment depression (>3 mm), or uncontrolled arrhythmia
- Room air SpO2 (oxygen saturation) at rest or with exercise qualifying for supplementary oxygen (SpO2≤88%)
- Abnormal kidney or liver function (2x upper limit of normal);
- eGFR 140 mg/dl);
- Deficient levels of vitamin D (25 hydroxyvitamin D level 14 drinks/week)
- Unstable severe depression
- Regular use of: growth hormones, oral steroids, weight loss medications or prescription osteoporosis meds
- Current participation in other research study
Data sourced from ClinicalTrials.gov (NCT02923674). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.