N/A
Completed N=63
High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
Desaturation of Blood · Obesity · Colonoscopy · sleep apnea
Source: ClinicalTrials.gov NCT03148262 ↗
Enrolled (actual)
63
Serious AEs
0.0%
Results posted
Nov 2018
Primary outcomePrimary: The Number of Desaturation Episodes — 0; 0 Episodes
Summary
It is standard practice in the United States and many parts of world to perform Gastrointestinal (GI) endoscopy with the patient under deep sedation. Obesity is accepted as a patient specific risk factor for hypoxic events during procedural sedation for GI endoscopic procedures. The Obese population has a higher prevalence of obstructive sleep apnea (OSA) which is characterized by repeated obstruction of the upper airway, and leads to apnea and desaturation. This prospective, randomized study was designed to compare the effectiveness of the high flow nasal cannula and the standard nasal cannula in morbidly obese (BMI > 40) patients receiving deep intravenous sedation during colonoscopies. This study will assess whether use of the high flow nasal cannula (HFNC) leads to less intraoperative desaturation events compared to the current standard of care.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Number of Desaturation Episodes |
0; 0 | — |
Eligibility Criteria
Inclusion Criteria
- Age between 18-80
- Subjects undergoing colonoscopies
- Morbidly obese BMI ≥ 40
Exclusion Criteria
- Subjects deemed hemodynamically unstable by the anesthesia team
- Subjects who are an aspiration risk and will require endotracheal intubation.
- Pregnancy
- Subjects with an allergy to propofol
- Patients who are unable to tolerate the high flow nasal cannula secondary to discomfort
- Subjects unwilling to sign consent
- Chronic obstructive pulmonary disease
- Patients that received medications other than lidocaine and propofol
Data sourced from ClinicalTrials.gov (NCT03148262). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.