N/A
N=190
Opioid Prescribing After Cesarean Delivery
Surgery · Opioid Use
Bottom Line
View on ClinicalTrials.gov: NCT03168425 ↗Enrolled (actual)
190
Serious AEs
0.5%
Results posted
Jun 2019
Primary outcome: Primary: Unused Opioids — 5; 10 oxycodone 5mg tablets
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Tailored prescription (Other); Control (Other)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Vanderbilt University Medical Center
- Primary completion
- Sep 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Unused Opioids |
5; 10 | — |
| SECONDARY Pain: Frequency That Participants Reported Uncontrolled Pain |
4; 3 | — |
Summary
The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic. This rise parallels a sharp increase in the amount of legal prescription opioids dispensed. The abundance of prescription opioids available is a primary pathway for opioid abuse and diversion. Adjusting post- cesarean delivery opioid prescribing practices to better match actual patient need has the potential to reduce unused opioids available for diversion, nonmedical use, and development of chronic dependence, as well as reduce wasted resources.
Eligibility Criteria
Inclusion Criteria
- Women 18-50 years old
- Women undergoing cesarean delivery at a single institution
Exclusion Criteria
- Major post-surgical complications: cesarean hysterectomy, bowl or bladder injury, reoperation, ICU admission, wound infection or separation
- Chronic opioid use: Taking buprenorphine during pregnancy, taking an opioid for > 7 days during pregnancy.
- Non English or Spanish speaking
Data sourced from ClinicalTrials.gov (NCT03168425). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.