N/A N=99 Treatment

Effects of Walking and Heating on Vascular Function in Diabetic Patients

Type 2 Diabetes Mellitus · Obesity

Bottom Line

View on ClinicalTrials.gov: NCT03203694 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2024

Primary outcome: Primary: Insulin-stimulated Leg Blood Flow Calculated as Percent Change (t0, t60) — 133.6; 8.92 percentage change

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Walking: Intervention arm in diabetics (Behavioral); Walking: No intervention in diabetics (Other); Walking: Healthy cohort as reference controls (Other); Lower body heating: Intervention arm in healthy subjects (Behavioral); Lower body heating: Intervention arm in diabetics (Behavioral); Lower body heating: Healthy cohort as reference controls (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Missouri-Columbia
Primary completion: Mar 2022

Outcome Measures

Outcome	Result	p-value
PRIMARY Insulin-stimulated Leg Blood Flow Calculated as Percent Change (t0, t60)	133.6; 8.92	—
PRIMARY Net Change in Insulin-stimulated Leg Blood Flow Calculated as Percent Change From Pre-intervention (t0,t60) to Post-intervention (t0,t60).	15.9; -17.6; 60.2; 11.1	—

Summary

The purpose of the present study is to determine the effects of increased walking and lower body heating on leg vascular function in patients with type 2 diabetes (T2D).

Eligibility Criteria

Inclusion Criteria

Patients with type 2 diabetes who are overweight and obese (BMI 25-50 kg/m2), 35 to 65 years of age, and sedentary ( 14 drinks/week for men; >7 drinks/week for women);

current tobacco use;
pregnancy;
mobility limitations;
foot ulcers;
diabetic neuropathy
uncontrolled hypertension (>=180 systolic / 100 diastolic mmHg)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03203694). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.