N/A
Completed N=15
Low Frequency Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease
Source: ClinicalTrials.gov NCT03204526 ↗Enrolled (actual)
15
Serious AEs
0.0%
Results posted
Jun 2021
Primary outcomePrimary: Mean Reaction Time for Computerized Color Naming Stroop Task — 5.09 seconds
Summary
Prospective trial of low frequency deep brain stimulation of the ventral subthalamic nucleus to improve cognitive performance in patients with advanced Parkinson's disease. All study participants have undergone DBS implantation surgery as part of their routine care for motor manifestations of Parkinson's disease. In this study, a temporary low frequency period of stimulation will be applied to determine its effects on cognition.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Reaction Time for Computerized Color Naming Stroop Task |
5.09 | — |
| PRIMARY Mean Accuracy Rates Using Computerized Color Naming Stroop Task |
4.61 | — |
| SECONDARY Number of Participants With Worsening Depression Using Beck's Depression Index |
— | — |
| SECONDARY Number of Participants Showing Motor Worsening Using the Unified Parkinson's Disease Rating Scale (UPDRS-III) |
— | — |
Eligibility Criteria
Inclusion Criteria
- Parkinson's disease, undergoing deep brain stimulation implantation as part of their routine management of motor symptoms.
Exclusion Criteria
Data sourced from ClinicalTrials.gov (NCT03204526). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.