Phase 3
Completed N=1,758
Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa
Source: ClinicalTrials.gov NCT03231358 ↗Enrolled (actual)
1,758
Serious AEs
0.0%
Results posted
May 2025
Primary outcomePrimary: Prevalence of HIV and/or Chlamydia and/or Gonorrhoeae — 60; 70 Participants
◆ Published Evidence
Not yet cited
0citations
Rationale and design of a randomized controlled trial testing the efficacy of Safe South Africa, an intervention to prevent HIV risk behavior and sexual violence among adolescent boys.
Summary
The purpose of this study is to test the efficacy of Our Family Our Future, an integrated intervention for preventing HIV and depression onset among adolescents.
Linked Publications
-
Rationale and design of a randomized controlled trial testing the efficacy of Safe South Africa, an intervention to prevent HIV risk behavior and sexual violence among adolescent boys.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Prevalence of HIV and/or Chlamydia and/or Gonorrhoeae |
60; 70 | — |
| PRIMARY Number of Participants Engaged In Vaginal Sex |
216; 280; 141; 166 | — |
| PRIMARY Depressive Symptoms |
18; 22 | — |
Eligibility Criteria
Inclusion Criteria
- 14-16 years
- adolescent concurs that the adult identified is their parent (to also include primary caregivers in the pa-rental role)
- when more than one child in the family falls within the eligible age range, one child will be chosen at random
- lives in the household at least 4 days a week
Exclusion Criteria
- no or low symptoms (<6) or clinically significant thresholds of depression (16+)
Data sourced from ClinicalTrials.gov (NCT03231358) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.