Phase 3
N=1,758
Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa
Human Immunodeficiency Virus · Depression · Sexually Transmitted Diseases
Bottom Line
View on ClinicalTrials.gov: NCT03231358 ↗Enrolled (actual)
1,758
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Prevalence of HIV and/or Chlamydia and/or Gonorrhoeae — 60; 70 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- Our Family Our Future (Behavioral)
- Age
- Pediatric · 14+ yrs
- Sex
- All
- Sponsor
- Brown University
- Primary completion
- Aug 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Prevalence of HIV and/or Chlamydia and/or Gonorrhoeae |
60; 70 | — |
| PRIMARY Number of Participants Engaged In Vaginal Sex |
216; 280; 141; 166 | — |
| PRIMARY Depressive Symptoms |
18; 22 | — |
Summary
The purpose of this study is to test the efficacy of Our Family Our Future, an integrated intervention for preventing HIV and depression onset among adolescents.
Eligibility Criteria
Inclusion Criteria
- 14-16 years
- adolescent concurs that the adult identified is their parent (to also include primary caregivers in the pa-rental role)
- when more than one child in the family falls within the eligible age range, one child will be chosen at random
- lives in the household at least 4 days a week
Exclusion Criteria
- no or low symptoms (<6) or clinically significant thresholds of depression (16+)
Data sourced from ClinicalTrials.gov (NCT03231358). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.