N/A
N=335
Vaccination Education Through Pharmacists and Senior Centers (VEPSC)
Infectious Disease · Pneumonia, Bacterial · Influenza · Zoster; Herpes
Bottom Line
View on ClinicalTrials.gov: NCT03239665 ↗Enrolled (actual)
335
Serious AEs
—
Results posted
Jul 2020
Primary outcome: Primary: Mean Change in Knowledge and Awareness About Vaccine-Preventable Diseases — 3.5; 4.9; 1.3; 1.8 Scores on a scale — p=0.0081
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Pharmacist-led Intervention (PHARM) (Behavioral); Peer-led Intervention (PEER) (Behavioral)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- Rutgers, The State University of New Jersey
- Primary completion
- Sep 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Change in Knowledge and Awareness About Vaccine-Preventable Diseases |
3.5; 4.9; 1.3; 1.8; 1.5; 1.9 | 0.0081 sig |
| SECONDARY Within-Group Changes in Beliefs About Vaccine-Preventable Diseases and Vaccines |
1; 0; 0; 0; 3; 1 | 0.0011 sig |
| SECONDARY Cost Analysis |
7392.94; 14887.45; 50.29; 106.34; 1232.16; 1240.62 | — |
| SECONDARY Number of Participants Reporting Program Satisfaction |
124; 127; 2; 3; 21; 10 | 1.0 |
| SECONDARY Number of Participants Planning to Receive Each Vaccine |
26; 36; 46; 58; 75; 46 | 0.7728 |
| SECONDARY Number of Participants Reporting Positive Vaccination Status at Each Timepoint |
50; 32; 80; 98; 17; 10 | 0.0163 sig |
| SECONDARY Number of Participants Planning to Discuss Vaccines With Others as Assessed by the Activation Questionnaire |
66; 67; 81; 73; 98; 95 | 0.6153 |
| SECONDARY Number of Participants Having Discussed Vaccines With Others at One-month Follow-up as Assessed by the Activation Questionnaire |
22; 62; 125; 78; 7; 23 | <0.0001 sig |
Summary
The study consists of two arms (PHARM and PEER) designed to educate participants about three vaccine-preventable diseases (zoster, pneumonia, and influenza) and vaccination. PHARM will consist of a 60-minute presentation about the three vaccine-preventable diseases and their vaccinations delivered by a pharmacist, featuring a didactic lecture and discussion supplemented by video clips of community members discussing their experiences around vaccination, as well as physicians underscoring the importance of vaccination. PEER will consist of a 60-minute small-group session led by a peer educator which includes scripted roleplaying exercises designed to reinforce learnings pertaining to these three vaccine-preventable diseases and their vaccinations. The components of these interventions will be designed to address specific barriers to vaccination identified by literature search and our prior work in the area of community-based vaccine education. Both arms will focus primarily on pneumococcal disease and zoster but will include limited content on influenza because participants are likely to have questions about how the flu and its vaccination differ from pneumococcal diseases and zoster. The study will be implemented in an older, predominantly African-American (AA) population, consistent with our prior work in this area.
Eligibility Criteria
Inclusion Criteria
- Age ≥50;
- Can attend a 2-hour session (though both PHARM and PEER entail 60 minutes of intervention, an additional hour is needed to allow for informed consent and data collection);
- Speak and read English at ≥4th grade level as determined by a brief reading passage;
- Cognitively intact as evidenced by an Abbreviated Mental Status Test score ≥7.
Exclusion Criteria
- Failure to meet inclusion criteria
- Failure to give informed consent to participate in the study
Data sourced from ClinicalTrials.gov (NCT03239665). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.