AI-driven in silico tools enhance sequence design and optimization for monoclonal antibody development
Artificial intelligence speeds up discovery of new antibody treatments
This systematic review evaluates AI-driven in silico tools for the discovery and optimization of monoclonal antibodies across infectious, au…
New computer tools powered by AI help scientists design and optimize antibodies for diseases like cancer and autoimmune disorders faster.
CAR technology for autoimmune disorders, infectious diseases, fibrotic lesions, inflammatory bowel disease, and type 1 diabetes is reviewed
Chimeric antigen receptor technology may help treat autoimmune disorders and other conditions
This narrative review discusses the application of chimeric antigen receptor (CAR) technology across autoimmune disorders, infectious diseas…
A narrative review suggests chimeric antigen receptor technology could be useful for treating autoimmune disorders, infectious diseases, and…
Narrative review explores bromelain's potential across multiple chronic diseases
Bromelain shows promise for several diseases but needs more human testing
This narrative review examines bromelain's potential in cancer, cardiovascular, metabolic, infectious, and neurodegenerative diseases. Most …
Bromelain looks promising for managing cancer and other conditions, yet current evidence mostly comes from lab and animal work.
Narrative review evaluates Oxford Nanopore sequencing for pediatric infectious disease diagnostics
New Pocket Device Finds Kids' Infections in Hours Not Days
This narrative review examines the use of Oxford Nanopore Technologies (ONT) sequencing in pediatric emergency infectious diseases. The auth…
• Real-time gene sequencing spots infections and antibiotic needs fast • Helps doctors treat seriously sick children in emergency rooms • St…
Review of phage strategies for antimicrobial resistance and cancer-related infections
Virus Trucks Deliver Cancer Drugs While Fighting Superbugs
This narrative review examines phage-enabled strategies, tailored formulations, and engineered phages for treating antimicrobial resistance,…
• Engineered viruses now target tumors and kill drug-resistant bacteria • Patients with tough infections or hard-to-treat cancers could bene…
Community-based intervention reduces antibiotic use in Burkina Faso and DRC
New Plan Cuts Dangerous Antibiotic Use in African Villages
In this cluster randomised controlled trial across 44 villages in Burkina Faso and Democratic Republic of Congo, a community-based behaviour…
A simple community plan successfully lowered the use of strong antibiotics in rural Africa.
Chronic Insomnia in Hospitalized Adults: Associated Conditions and Metabolic Abnormalities
Elderly women with insomnia often have heart disease, infections, and metabolic issues
This retrospective observational study evaluated 871 hospitalized adults aged 18 to 100 years with chronic insomnia at a single center in Ch…
Hospitalized older women with insomnia frequently face infections, heart disease, and blood sugar problems, a single-center study finds.
Metagenomic next-generation sequencing shows higher sensitivity than conventional tests for pediatric infectious disease diagnosis
New test may help find infections in children but has limits
This systematic literature review and meta-analysis evaluated diagnostic accuracy in pediatric patients (≤21 years) with suspected infectiou…
A new test finds infections in sick children 84% of the time, nearly doubling the success rate of standard lab tests that only catch them 40…
Explainable AI methods may address black-box limitations in clinical microbiology and infectious diseases
Review explores how explainable AI could help in infectious disease medicine
A narrative review examines Explainable AI (XAI) methods in clinical microbiology, infectious diseases, and public health.
Explainable AI tools could help doctors trust computer decisions in fighting infectious diseases, but current systems remain too opaque for …
Systematic review finds first FDA-approved CRISPR therapy and broader clinical trial exploration
First CRISPR gene therapy approved for blood disorders, with broader research underway
A systematic review of clinical trials registered at clinicaltrials.gov found the first CRISPR-Cas9 therapy obtained FDA approval in late 20…
The first CRISPR gene therapy is approved for sickle-cell anemia and β-thalassemia, with ongoing trials exploring its use for cancer and inf…
Systematic review examines PI3K/Akt-mTOR pathway role in host defense and pathogen evasion
How do germs outsmart our immune system? A key cellular pathway holds clues
A systematic review synthesizes research on the PI3K/Akt-mTOR signaling pathway in infectious diseases.
Our immune system fights infection by activating a key cellular switch, but clever germs hijack the same control panel to hide and survive i…
Questions about Infectious Diseases
Does the review mention bromelain use in infectious disease animals?
The provided reviews mention bromelain's potential in infectious diseases but note that most evidence comes from animal and lab studies rather than human trials.
Full answer →Are there clinical trials for CRISPR therapy in infectious disease?
Yes, clinical trials for CRISPR therapy in infectious disease are currently being explored, alongside trials for other conditions like cancer and sickle-cell anemia.
Full answer →Is metagenomic sequencing better than conventional tests for pediatric infectious disease?
Metagenomic sequencing finds more infections in children than conventional tests, but doctors must still interpret results carefully to avoid false alarms.
Full answer →Does the PI3K/Akt-mTOR pathway play a role in how my body fights infection?
The PI3K/Akt-mTOR pathway is a central signal network that helps your immune cells fight infection, but germs also try to block it to survive.
Full answer →How might explainable AI improve my diagnosis for an infectious disease?
Explainable AI helps doctors see exactly why an AI model suggests a specific infectious disease diagnosis, reducing errors from 'black-box' models and building trust in complex cases.
Full answer →