N/A
N=534
Charge: A Text Messaging-based Weight Loss Intervention
Weight Loss · Obesity
Bottom Line
View on ClinicalTrials.gov: NCT03254940 ↗Enrolled (actual)
534
Serious AEs
0.0%
Results posted
Apr 2025
Primary outcome: Primary: Average Weight Change — 0.1; -0.4; -3.4; -0.8 Weight in kg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Charge (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Duke University
- Primary completion
- Jun 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Average Weight Change |
0.1; -0.4; -3.4; -0.8; -3.3; -1.3 | — |
| SECONDARY Change in Diet |
0.8; 2; 4.4; 1.2; 3.8; 2.6 | — |
| SECONDARY Average Change in Physical Activity |
202.2; 103.8; 256.8; 335.6; 88.6; 241.5 | — |
Summary
This study evaluates different versions of a text messaging-based app for weight loss. This study will place participants to 1 of 32 experimental conditions that reflect different texting components and levels. Participants will be randomized to a condition. The investigators will recruit 448 adults into a 6-month weight loss program, with an additional follow-up 6-months after the intervention ends.
Eligibility Criteria
Inclusion Criteria
- males and females aged 18-65 years
- participants have English language proficiency
- participants have a BMI between 25-40 kg/m2
- Participants will own a smartphone
- Participants will be willing to receive multiple text messages daily.
Exclusion Criteria
- prior or planned bariatric surgery
- psychiatric hospitalization in past 12 months
- pregnancy, nursing, or planned pregnancy
- history of a cardiovascular event
- history of an eating disorder
- history of a condition (e.g., end stage renal disease, cancer, schizophrenia) or use of medications (e.g., lithium, steroids, anti-psychotics) that would affect weight measurement, for which weight loss is contraindicated, or might promote weight change
- current participation in a weight loss trial and/or recent weight loss > 10%
- investigator discretion for safety reasons
Data sourced from ClinicalTrials.gov (NCT03254940). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.