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N/A N=47,396 Randomized Supportive Care

Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support

Alzheimer Disease · Dementia

Enrolled (actual)
47,396
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Hospital Transfers — 1.2; 1.3 number of hospital transfers — p=0.3313

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
APPROACHES ACP Specialist Program (Behavioral); Standard of care (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Indiana University
Primary completion
Aug 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Hospital Transfers
1.2; 1.3 0.3313
SECONDARY
Hospice Enrollment
1095; 1181 0.3327
SECONDARY
Death in Hospital
163; 146 0.3946

Summary

Nursing home (NH) patients with Alzheimer's disease and related dementias often receive unwanted, burdensome treatments such as hospitalization. Advance care planning (ACP) is a key strategy to support patients and family-caregivers in making informed decisions and ensuring treatment preferences are proactively known and honored. The ACP Specialist Program will improve care and reduce unwanted, burdensome hospitalizations through improved ACP procedures, standardized staff education on ACP, and systematic ACP facilitation delivered by existing NH staff.

Eligibility Criteria

Inclusion Criteria

  • Facilities are owned by NH corporate partners
  • Facilities are Medicare/Medicaid-certified
  • Facilities have an electronic medical records system
  • Minimum bedsize of 50 or more;
  • At least 50% long-stay as defined by a length of stay of 100 days or longer.

Exclusion Criteria

  • Problematic or unstable facilities will be removed in consultation with NH corporate leaders prior to randomization
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03323502). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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