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N/A N=455 Randomized Single-blind Prevention

Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults

Suicidal Ideation

Enrolled (actual)
455
Serious AEs
23.3%
Results posted
Apr 2025
Primary outcome: Primary: Suicide Attempts, as Measured by the Columbia Suicide Severity Rating Scale (CSSRS) — 13; 17; 24; 28 Participants — p=0.58

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Peer mentorship (Behavioral); Enhanced Usual Care (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Michigan
Primary completion
Sep 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Suicide Attempts, as Measured by the Columbia Suicide Severity Rating Scale (CSSRS)
13; 17; 24; 28 0.58
PRIMARY
Suicidal Ideation (Current), as Measured by the Beck Suicide Scale (BSS)
4.15; 4.37; 4.86; 4.25 0.46
SECONDARY
Suicide Attempts (Measured by the Medical Record)
11; 9 0.18
SECONDARY
Self Efficacy to Avoid Suicidal Action (Measured by the Self Efficacy to Avoid Suicidal Action Scale)
36.12; 34.64; 37.06; 35.52 0.29
SECONDARY
Suicidal Ideation (Worst-point), as Measured by the Beck Scale for Suicidal Ideation (BSS)
10.66; 10.53; 7.76; 8.68 0.35

Summary

This is a single-blind, randomized controlled trial to test the effectiveness of a peer mentorship intervention (PREVAIL) for reducing suicide risk compared to enhanced usual care among participants (N=455) at high-risk for suicide recruited from inpatient psychiatric units.

Eligibility Criteria

Inclusion Criteria

  • are age 18 years or older,
  • are currently admitted to an inpatient psychiatric unit and have medical record documentation of suicidal ideation or suicide attempt at the time of admission,
  • have a Beck Suicide Scale score of 5 or higher for the 1-week period prior to admission,
  • are fluent in English,
  • are able to be reached reliably by telephone.

Exclusion Criteria

  • substantially cognitively impaired (according to the Mini-Cog),
  • unable to provide informed consent for any reason (including incompetency),
  • determined by the patient's attending psychiatrist that peer mentorship is not appropriate due to unstable psychosis, cognitive disorder, or severe personality disorder,
  • already receiving or intending to receive peer mentorship (i.e., sponsor from Alcoholics Anonymous) or group-based peer support on a biweekly or more frequent basis,
  • residing more than 50 miles from any peer mentor,
  • planning to be discharged to another inpatient or residential facility, or
  • receiving electroconvulsive therapy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03373916). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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