Phase 2 N=247 miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
Major Depressive Disorder
Primary: Beck Scale for Suicide Ideation (BSS) — 9.09; 8.46; 1.9 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=103 Reducing Suicidal Ideation Through Insomnia Treatment
Insomnia · Depression · Suicidal Ideation
Primary: Scale for Suicide Ideation Index (SSI) — 4.66; 5.25 units on a scale
N/A N=118 Virtual Hope Box - Effectiveness of a Smartphone App for Coping With Suicidal Ideation
Suicidal Ideation · Thoughts of Self Harm · Coping
Primary: Beck Scale for Suicidal Ideation — 3.31; 3.58 units on a scale
N/A N=157 Improving Treatment Outcomes for Suicidal Veterans With PTSD
Suicidal Ideation · Suicide, Attempted · Ptsd
Primary: Change in Suicide Ideation — 5.91; 6.37; 3.67; 2.47 units on a scale
Phase 4 N=75 Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation
Suicidal Ideation
Primary: Change From Baseline in Columbia-Suicide Severity Rating Scale (C-SSRS) — 13.69; 14.46; 8.27; 10.87 score on a scale
N/A N=284 Southwest Hub for American Indian Youth Suicide Prevention Research
Suicide · Surveillance · Mental Health
Primary: Suicide Ideation Questionnaire (SIQ) — 10.2; 10; 10.1; 10.1 Z-score
N/A N=64 Suicide Prevention Intervention for Vulnerable Emerging Adult Sexual Minorities
Suicide
Primary: Suicidal Ideation and Behavior — 2.625; 2.34375; 1.37931; 1.064516 Mean Units on the CSSRS SI scale
Phase 4 N=20 Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder · Suicidal Ideation · Nightmares
Primary: Change Score for Scale for Suicide Ideation — 7.6; 8.2 units on a scale
N/A N=68 Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification
Depression · Bipolar Disorder · Anxiety Disorders
Primary: Clinical Global Improvement Scale (CGIS) — 14; 20 Participants
N/A N=152 Brief Cognitive Behavioral Therapy for Military Populations
Suicide · Suicidal Ideation
Primary: Estimated Percentage of Participants Making Suicide Attempt During 24-month Follow-up — 13.8; 40.2 estimated percentage w/ suicide attempt — p=.02
N/A N=25 Nurse Suicide: Physiologic Sleep Health Promotion Trial
Suicide · Nurse's Role · Work Environment Adverse Effects
Primary: Columbia Suicide Severity Rating Scale (Intensity of Ideation) - Number of Participants With a Positive CSSRS Ideation — 2 Participants
N/A N=60 Telehealth to Reduce Suicidality and Improve HIV Care Engagement in Tanzania
Suicide · Suicidal Ideation · HIV Infections
Primary: Number of Participants With Suicidal Ideation — 4; 3; 0; 0 Participants — p=0.961
N/A N=84 CAMPUS - Feasibility Sub-Study
Suicide
Primary: Number of Eligible Students Who Agree to Randomization — 8; 24; 20; 16 Participants
N/A N=8 Brief Suicide Intervention for Youth in Juvenile Detention Settings
Suicide Prevention
Primary: Number of Participants Who Reported Suicide Attempts as Measured by the Columbia Suicide Severity Rating Scale (C-SSRS) — 1 Participants
Phase 3 N=230 54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide
Depressive Disorder, Major
Primary: Change From Baseline in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score at 24 Hours Post First Dose (Last Observation Carried Forward [LOCF] Data)…