N/A
Completed N=349
In Vitro Fertilization Impact on Metabolic Parameters
Source: ClinicalTrials.gov NCT03426228 ↗Enrolled (actual)
349
Serious AEs
0.0%
Results posted
Jul 2021
Primary outcomePrimary: Short-term Effect of Fertility Medications on Glucose Homeostasis and Insulin Resistance in Patients Undergoing IVF Treatment — 87.62; 82.19; 9.37; 9.45 mg/dL
Summary
A quantitative prospective cohort study will be conducted, where blood samples will be collected at different timings during the IVF protocol, to assess the impact of fertility medications on metabolic parameters of patients undergoing IVF treatment.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Short-term Effect of Fertility Medications on Glucose Homeostasis and Insulin Resistance in Patients Undergoing IVF Treatment |
87.62; 82.19; 9.37; 9.45 | — |
| SECONDARY Effect of Fertility Medications on Lipids Profile |
199.5; 174.9 | — |
| SECONDARY Effect of Fertility Medications on Thyroid Function |
1.36; 1.80 | — |
Eligibility Criteria
Any patient presenting to us for fresh IVF with the following:
Inclusion Criteria
- Presenting with or without PCOS
- Presenting with structural or mechanical infertility, such as fallopian tube obstruction, endometriosis, fibroids
- Presenting with male factor
- Presenting with or without insulin resistance
- Combination of more than one of the listed above criteria
Exclusion Criteria
- Pre-diabetes or diabetes patients (confirmed by impaired or abnormal OGTT)
- Age above 39 years of age
- Taking glucose-lowering meds, such as metformin or janumet.
- Taking corticosteroids
Data sourced from ClinicalTrials.gov (NCT03426228). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.