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N/A N=638 Randomized Prevention

Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)

Smoking · Tobacco Use

Enrolled (actual)
638
Serious AEs
0.2%
Results posted
Sep 2023
Primary outcome: Primary: E-cig Use at End of Sampling Period — 13; 72 percentage of participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Electronic Cigarette (Behavioral)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
Medical University of South Carolina
Primary completion
Sep 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
E-cig Use at End of Sampling Period
13; 72
SECONDARY
Conversion
20; 19
SECONDARY
Smoking Cessation
8; 14

Summary

The purpose of this study is to measure changes in smoking behavior during and following sampling of an e-cigarette product. E-cigarettes are classified by the US Food and Drug Administration (FDA) as a tobacco product, though they contain no tobacco. Unlike regular cigarettes, which are burned (creating smoke that is inhaled), e-cigarettes include a heating element that vaporizes nicotine. E-cigarettes are likely much safer than conventional cigarettes, but they may not be entirely safe. We are testing the effects of one specific ecigarette (NJoy) on naturalistic changes in smoking behavior. Neither the tobacco industry nor any ecigarette manufacturer provides support of any kind to this study. There is no requirement to quit smoking in this study, nor is there any requirement to use e-cigarettes.

Eligibility Criteria

Inclusion Criteria

  • age 21+,
  • current smoker
  • regular use of email OR capacity to receive SMS text and internet access
  • additional smoking and health criteria determined at screening
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03453385). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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