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N/A Completed N=109 Randomized Double-blind Treatment

Peer Social Support During In Vivo Exposure for PTSD

Stress Disorders, Post-Traumatic · Anxiety · Mental Disorder · Traumatic Disorder
Source: ClinicalTrials.gov NCT03485391 ↗
Enrolled (actual)
109
Serious AEs
0.0%
Results posted
Aug 2024
Primary outcomePrimary: Clinical Administrated PTSD Scale (CAPS) — 25.44; 24.44 score on a scale

Summary

Veterans who have prematurely dropped out of exposure therapy for PTSD will be contacted and offered the opportunity to return to treatment, this time with the assistance of an in vivo exposure therapy 'workout buddy'. This peer will meet them at the in vivo exposure therapy location and offer support an encouragement while the patient remains in that location. As the PTSD treatment standards in Charleston and other VA sites across the country increasingly include telemedicine delivered care, both in person and telemedicine based exposure therapy recipients will be included. There will be no randomization; all participants will receive the peer support 'workout buddy' for exposure therapy assignments.

Outcome Measures

OutcomeResultp-value
PRIMARY
Clinical Administrated PTSD Scale (CAPS)
25.44; 24.44
SECONDARY
PTSD Checklist, 5th Version (PCL-5)
40.2105; 37.1678
SECONDARY
Patient Health Questionnaire (PHQ-9)
12.5554; 12.2859
SECONDARY
Combat Exposure Scale (CES)
4.1132; 5.2400

Eligibility Criteria

Participant Inclusion Criteria:

  • Adult male or female over the age of 18 that has served, or is currently serving in the military.
  • Either diagnosis of PTSD as determined by a Clinician Administered PTSD Scale for DSM-5 (CAPS-5) clinical interview or CAPS-5 severity ≥ 25, and a PCL-5 score of ≥25.
  • Attempted PE treatment in the past, but did not complete treatment (defined as dropping out from treatment or refusal to engage in in vivo exposure assignments) OR identified as "at-risk" of dropping out of current exposure therapy treatment (defined as failure to complete 3 sessions of therapy within any 6 week period or verbally indicating that they are not comfortable with the exposure activities).

Participant Exclusion Criteria:

  • Active psychosis or dementia at screening.
  • Suicidal ideation with clear intent.
  • Concurrent enrollment in another clinical trial for PTSD or depression.

Peer Inclusion Criteria:

  • Adult male or female over the age of 18 that has served, or is currently serving, in the military.
  • Successful competition of exposure therapy treatment in the past and willingness to act as peer in the program.
  • PCL-5 score of 32 or lower.

Peer Exclusion Criteria:

  • Active psychosis or dementia at screening.
  • Suicidal ideation with clear intent.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03485391). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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