N/A
N=65
Addictive Potential of LCCs in Dual Users
Tobacco Use Disorder · Dual Tobacco Use · Tobacco Dependence · Smoking · Smoking, Cigar
Bottom Line
View on ClinicalTrials.gov: NCT03496077 ↗Enrolled (actual)
65
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Demand Elasticity — 0.027; 0.032 cigarettes/dollar
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Flavored and unflavored little cigars/cigarillos (LCCs) (Other)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- UConn Health
- Primary completion
- Dec 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Demand Elasticity |
0.027; 0.032 | — |
| PRIMARY Demand Intensity |
4.193; 3.898 | — |
Summary
This study is about whether or not little cigars and cigarillos cause or maintain addiction, and if flavors, such as fruit, make them more addictive. The purpose of this study is to understand the addiction potential of little cigars and cigarillos compared to cigarettes in young adults who smoke both products. This study will also look at the differences between men and women. In the rest of this form, little cigars or cigarillos will be referred to as LCCs.
Eligibility Criteria
Inclusion Criteria
- Current regular dual user of little cigars/cigarillos (LCCs) and cigarettes, defined as: (a) report smoking cigarettes on ≥ 8 of the past 30 days, and (b) report smoking unaltered LCCs (without marijuana) on ≥ 8 of the past 30 days.
- Able to speak, read and understand English
- Age 18-34 years of age
- Stable residence (not planning to move during study period)
- Not intending to quit smoking cigarettes or LCCs within the next 2 weeks
- An expired carbon monoxide (CO) level of at least 4 ppm of expired air to verify smoking status
Exclusion Criteria
- Pregnant for women (verified by urine pregnancy test at Visits 1 and 2)
- Current use of (or plans to use in the next 2-3 weeks) nicotine replacement products or cessation products (e.g., bupropion) to minimize confounding effects of another product)
- Positive breath alcohol screen (breath alcohol level (BAL) > 0 g/ml; one re-test allowed; assessed at Visits 1, 2, and 3)
- Illicit drug use other than marijuana (verified by positive drug toxicology test at Visits 1 and 3; one re-test allowed)
- Met criteria for Cannabis Dependence assessed by the Cannabis Use Disorders Identification Test-Revised (CUDIT-R)
Data sourced from ClinicalTrials.gov (NCT03496077). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.