N/A
N=184
Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being
Depressive Symptoms · Stress, Psychological
Bottom Line
View on ClinicalTrials.gov: NCT03506945 ↗Enrolled (actual)
184
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Center for Epidemiologic Studies Depression Scale--Revised (CESD-R) — 16.9; 14.9 Score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- mPEP (Behavioral); Bibliotherapy (Behavioral)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- University of California, San Diego
- Primary completion
- May 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Center for Epidemiologic Studies Depression Scale--Revised (CESD-R) |
16.9; 14.9 | — |
| SECONDARY Positive and Negative Affect Scale (PANAS) |
30.0; 29.8; 20.4; 19.5 | — |
| SECONDARY Blood Pressure |
123.4; 121.3; 75.8; 76.0 | — |
| SECONDARY Dementia Quality of Life Scale for Older Family Carers (DQoLOC) |
63.5; 64.8 | — |
Summary
Caregivers suffer great amounts of distress that significantly impacts their mental and physical well-being, yet caregivers' access to quality, evidence-based care is currently very limited. The public health significance of the proposed study is that our internet and mobile-based web intervention will (1) significantly reduce caregiver distress and improve caregivers' overall well-being, and (2) dramatically increase caregivers' access to high quality, evidence-based care at relatively low cost.
Eligibility Criteria
Inclusion Criteria -
- English-speaking
- Spouse or Child Caregiver of a loved-one with Alzheimer's Disease or Related Dementia (ADRD)
- Aged 40 years or older at the time of enrollment
- Providing at least 20 hours of in-home care per week
- Screening positive for mild depressive symptoms (CESD-R≥16).
Exclusion Criteria -
- Diagnosed with a terminal illness
- Demonstrates cognitive impairment (MMSE 200/120 mm Hg)
- Participating in another active caregiver intervention (other than support groups)
- Receiving psychiatric care for serious mental illnesses such as schizophrenia or bipolar disorder
Data sourced from ClinicalTrials.gov (NCT03506945). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.