N/A
Completed N=44
Digital Cognition in Multiple Sclerosis
Source: ClinicalTrials.gov NCT03569618 ↗Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Oct 2020
Primary outcomePrimary: Change in Processing Speed After 6 Weeks of Treatment With a Digital Therapeutic 'Game 1', vs. 'Game 2'. — 6.10; 3.55 score on a scale
Summary
A DIGITAL THERAPEUTIC TO IMPROVE THINKING IN MULTIPLE SCLEROSIS
WHO: 65 participants with a confirmed diagnosis of Multiple Sclerosis (MS)
WHY: Purpose of the study is to compare the effect of 2 tablet-based brain training digital tools on important components of thinking (cognition).
WHAT: Complete a set of tests (physical and cognitive) at baseline, 6 weeks and 14 weeks, and use one of two brain training tools on an iPad in your home, for 25 minutes a day, 5 days a week, for 6 weeks.
WHERE: UCSF WEILL INSTITUTE FOR NEUROSCIENCES (675 Nelson Rising Lane, San Francisco, CA)
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Processing Speed After 6 Weeks of Treatment With a Digital Therapeutic 'Game 1', vs. 'Game 2'. |
6.10; 3.55 | — |
| SECONDARY Number of Participants With at Least 4-point Increase in SDMT Above Their Baseline Value 8 Weeks After Treatment |
14; 7 | — |
Eligibility Criteria
Inclusion Criteria
- Adult men or women diagnosed with multiple sclerosis (MS) or clinically isolated syndrome (CIS)
- SDMT z-score range (-2 to +1)
- Wifi available in home
- Able to use a tablet (iPad)
- Able to attend 3 study visits in person.
Exclusion Criteria
- Clinician's assessment of visual, cognitive, or motor impairment that would preclude participation.
- A clinical relapse within the last 30 days.
- Steroid treatment for clinical relapse within the last 30 days.
Data sourced from ClinicalTrials.gov (NCT03569618). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.