N/A
N=42
Patient Morbidity After Palatal Free Gingival Grafts With or Without PRF Membranes Coverage
Postoperative Pain · Postoperative Complications · Gingival Recession
Bottom Line
View on ClinicalTrials.gov: NCT03685396 ↗Enrolled (actual)
42
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcome: Primary: Post-operative Pain: VAS — 20.00; 62 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Platelet rich fibrin ( PRF) (Biological); hemostatic agents with oxidized and regenerated cellulosa (Drug)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Azienda Ospedaliera San Paolo
- Primary completion
- Jul 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Post-operative Pain: VAS |
20.00; 62 | — |
| PRIMARY Post-operative Discomfort |
39; 60 | — |
| PRIMARY Post-operative Stress |
21; 50 | — |
| PRIMARY Post-operative Inability to Chew |
60; 60 | — |
Summary
This study evaluates postoperative morbidity of patients that undergo free gingival graft harvesting from palate with or without use of autogenous PRF (Platelet Rich Fibrin) membranes to cover the donor site.In the Test Group venous blood sampling was done in order to prepare PRF membranes used to cover the donor site, whereas in Control Group hemostatic agents with oxidized and regenerated cellulosa were used.
Eligibility Criteria
Inclusion Criteria
- FMPS (Full Mouth Plaque Score) and FMBS (Full Mouth Bleeding Score) < 20%,
- presence of two adjacent Miller's Class I and II recession defects on natural teeth (≥ 2mm in depth);
Exclusion Criteria
- contraindications for periodontal surgery
- taking medications or having diseases known to interfere with periodontal tissue health or healing and coagulation.
- smoking more than 10 cigarettes a day
- Gingival recessions on molar teeth were excluded.
Data sourced from ClinicalTrials.gov (NCT03685396). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.