N/A
N=30
Effect of Aging on Cortical Excitability and Motor Learning
Aging
Bottom Line
View on ClinicalTrials.gov: NCT03750903 ↗Enrolled (actual)
30
Serious AEs
0.0%
Results posted
Apr 2025
Primary outcome: Primary: Magnetic Resonance Spectroscopy — 0.41; -0.29 ppm — p=0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Aerobic Exercise (Behavioral); Stretching and Balance Training (Behavioral)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Sep 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Magnetic Resonance Spectroscopy |
0.41; -0.29 | 0.05 |
Summary
The objective of the current proposal is to identify 1) how aging-related changes in GABAergic cortical inhibition affect motor performance, and 2) how aerobic exercise may improve inhibitory function and facilitate motor learning.
Eligibility Criteria
Inclusion Criteria
- living persons aged 50-85
Exclusion Criteria
- unmanaged diabetes
- participants completing vigorous exercise per week
- participants whose profession requires vigorous physical labor
- contraindication to magnetic resonance imaging
Data sourced from ClinicalTrials.gov (NCT03750903). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.